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Pennsaid (diclofenac topical) Drug Interactions

A total of 165 drugs are known to interact with Pennsaid (diclofenac topical).

  • 6 major drug interactions
  • 159 moderate drug interactions

Show all medications in the database that may interact with Pennsaid (diclofenac topical).

Check for interactions with Pennsaid (diclofenac topical)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Pennsaid (diclofenac topical)

  • Aleve (naproxen)
  • amlodipine (Norvasc)
  • Celebrex (celecoxib)
  • cyclobenzaprine (Flexeril, Amrix, Fexmid, Comfort Pac with Cyclobenzaprine)
  • Cymbalta (duloxetine)
  • folic acid (Folvite, FA-8, Folacin-800, FaLessa)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Proprinal, Motrin IB, Children's Motrin, IBU-200, Advil Migraine, Ibu-8, Motrin Childrens, Nuprin, Motrin Migraine Pain, Ibuprofen PMR, NeoProfen, Caldolor, Advil Children's, Addaprin, Motrin Infant Drops, Advil Infant's Concentrated Drops, Rufen, Genpril, A-G Profen, Ibu-Tab, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, Childrens Ibuprofen Berry, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Unithroid, Levothyrox, Euthyrox, Levo-T, L Thyroxine Roche, Eutroxsig, Novothyrox, Oroxine, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • Lyrica (pregabalin)
  • magnesium oxide (Mag-Ox 400, Mag-Oxide, Mag-Ox, Mag-200, Uro-Mag, MagGel, Phillips' Cramp-free, Mag-Caps)
  • meloxicam (Mobic, Vivlodex, Qmiiz ODT)
  • metformin (Glucophage, Glucophage XR, Glumetza, Riomet, Fortamet)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • prednisone (Deltasone, Rayos, Sterapred, Sterapred DS, Prednicot, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • Synthroid (levothyroxine)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Larapam SR, Tramedo, Ryzolt, GenRx Tramadol, ConZip, Zydol, Tramal SR, Tramahexal, Zamadol, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Tylenol (acetaminophen)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)
  • Voltaren Gel (diclofenac topical)
  • Zyrtec (cetirizine)

Pennsaid (diclofenac topical) alcohol/food interactions

There is 1 alcohol/food interaction with Pennsaid (diclofenac topical)

Pennsaid (diclofenac topical) disease interactions

There are 5 disease interactions with Pennsaid (diclofenac topical) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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