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Siltussin DM (dextromethorphan / guaifenesin) Drug Interactions

A total of 621 drugs are known to interact with Siltussin DM (dextromethorphan / guaifenesin).

  • 99 major drug interactions
  • 519 moderate drug interactions
  • 3 minor drug interactions

Show all medications in the database that may interact with Siltussin DM (dextromethorphan / guaifenesin).

Check for interactions with Siltussin DM (dextromethorphan / guaifenesin)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Siltussin DM (dextromethorphan / guaifenesin)

  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Ecotrin Adult Low Strength, Bufferin, Aspiritab, Arthritis Pain, Fasprin, Halfprin, Easprin, Durlaza, Aspirtab, St. Joseph 81 mg Chewable Aspirin, Aspergum, Low Dose ASA, Buffered Aspirin, Ecotrin Maximum Strength, Ascriptin Enteric, Acuprin 81, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Aspirin Lite Coat, Bayer Aspirin Regimen, Aspi-Cor, Empirin, Bayer Children's Aspirin, Bufferin Extra Strength, St. Joseph Aspirin, Bayer Women's Aspirin With Calcium, Miniprin, Migralex, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Bayer Aspirin Extra Strength Plus, Buffex, Entercote, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Ecpirin, Zero-Order Release, YSP Aspirin, Heartline, Bayer Advanced Aspirin, Buffasal)
  • azithromycin (Zithromax, Azithromycin Dose Pack, Z-Pak, Zmax)
  • Cardizem CD (diltiazem)
  • Claritin (loratadine)
  • diltiazem (Cardizem, Cartia XT, Diltiazem Hydrochloride SR, Cardizem CD, Diltiazem Hydrochloride CD, Diltiazem Hydrochloride XR, Taztia XT, Dilt-XR, Tiazac, Diltia XT, Matzim LA, Cardizem LA, Diltiazem Hydrochloride XT, Dilacor XR, Diltzac, Cardizem SR, Cardizem Monovial, Tiadylt ER)
  • Estrace (estradiol)
  • Lantus (insulin glargine)
  • Lyrica (pregabalin)
  • metformin (Glucophage, Glucophage XR, Glumetza, Riomet, Fortamet)
  • Novolog (insulin aspart)
  • ofloxacin (Floxin, Floxin IV)
  • ofloxacin ophthalmic (Ocuflox)
  • Pataday (olopatadine ophthalmic)
  • Patanol (olopatadine ophthalmic)
  • Prandin (repaglinide)
  • prednisone (Deltasone, Rayos, Sterapred, Sterapred DS, Prednicot, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • Tradjenta (linagliptin)
  • triamcinolone topical (Kenalog, Triderm, Kenalog in Orabase, Trianex, Aristocort A, Oralone, Rx Triamcinolone, Cinolar, Pediaderm TA, Dermasorb TA, Juulissa Pharmapak, DermacinRx Silazone, SilaLite Pak, Treziopak, DermacinRx Trizapak, Triacet, Aricin, Aristocort R, Delta-Tritex, Flutex, Cinalog)
  • Vitamin D3 (cholecalciferol)
  • Welchol (colesevelam)

Siltussin DM (dextromethorphan / guaifenesin) alcohol/food interactions

There is 1 alcohol/food interaction with Siltussin DM (dextromethorphan / guaifenesin)

Siltussin DM (dextromethorphan / guaifenesin) disease interactions

There is 1 disease interaction with Siltussin DM (dextromethorphan / guaifenesin):

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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