Skip to Content
Get key facts and figures about chronic dry eye

Drug interactions between dexamethasone ophthalmic and neomycin / polymyxin b ophthalmic

Results for the following 2 drugs:
dexamethasone ophthalmic
neomycin/polymyxin b ophthalmic

Interactions between your drugs

Major

neomycin polymyxin B sulfate

Applies to:

Using neomycin together with polymyxin B sulfate may increase the risk of serious side effects such as hearing loss, respiratory depression, and kidney problems. Patients who may be particularly susceptible include the elderly and those who are dehydrated or have preexisting kidney disease. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Let your doctor know immediately if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, or signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

neomycin neomycin topical

Applies to:

Both neomycin topical and neomycin belong to the same class of antibiotics known as aminoglycosides. Since the medication in neomycin topical may be absorbed from the skin, combining it with neomycin may increase the risk of serious side effects reported with aminoglycosides such as hearing loss, respiratory depression, and kidney problems. Patients who may be particularly susceptible include the elderly and those who are dehydrated or have preexisting kidney disease. Neomycin topical should generally not be used with neomycin in circumstances where significant absorption could occur (for example: application to burnt or broken skin; use of large quantities or on large areas for prolonged periods). Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Let your doctor know immediately if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, or signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Drug and food interactions

No results found in our database - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide