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Drug Interactions between Demadex IV and Keflex

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

cephalexin torsemide

Applies to: Keflex (cephalexin) and Demadex IV (torsemide)

Cephalosporin antibiotics like cephalexin can occasionally cause kidney problems, and using it with torsemide may increase that risk. The interaction is more likely to occur when the cephalosporin is given at high dosages by injection into the vein or when it is given to the elderly or individuals with preexisting kidney function impairment. Signs and symptoms of kidney damage may include nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Let your doctor know if you experience some or all of these problems during treatment. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

cephalexin food

Applies to: Keflex (cephalexin)

Cephalexin and multivitamin with minerals should not be taken orally at the same time. Products that contain zinc may interfere with the absorption of cephalexin into the bloodstream and reduce its effectiveness. You should take multivitamin with minerals at least three hours after taking cephalexin. Talk to a healthcare professional if you are not sure whether a product contains something that could potentially interact with your medication or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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