Drug Interactions between deferasirox and Elemental Iron
This report displays the potential drug interactions for the following 2 drugs:
- deferasirox
- Elemental Iron (carbonyl iron)
Interactions between your drugs
No interactions were found between deferasirox and Elemental Iron. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
deferasirox
A total of 589 drugs are known to interact with deferasirox.
- Deferasirox is in the drug class chelating agents.
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Deferasirox is used to treat the following conditions:
- Hemochromatosis (off-label)
- Hemosiderosis
- Iron Overload
- Thalassemia
Elemental Iron
A total of 86 drugs are known to interact with Elemental Iron.
- Elemental iron is in the drug class iron products.
- Elemental iron is used to treat Iron Deficiency Anemia.
Drug and food interactions
carbonyl iron food
Applies to: Elemental Iron (carbonyl iron)
ADJUST DOSING INTERVAL: Concomitant use of some oral medications may reduce the bioavailability of orally administered iron, and vice versa.
Food taken in conjunction with oral iron supplements may reduce the bioavailability of the iron. However, in many patients intolerable gastrointestinal side effects occur necessitating administration with food.
MANAGEMENT: Ideally, iron products should be taken on an empty stomach (i.e., at least 1 hour before or 2 hours after meals), but if this is not possible, administer with meals and monitor the patient more closely for a subtherapeutic effect. Some studies suggest administration of iron with ascorbic acid may enhance bioavailability. In addition, administration of oral iron products and some oral medications should be separated whenever the bioavailability of either agent may be decreased. Consult the product labeling for specific separation times and monitor clinical responses as appropriate.
References
- "Product Information. Feosol (ferrous sulfate)." SmithKline Beecham
- (2021) "Product Information. Accrufer (ferric maltol)." Shield Therapeutics
deferasirox food
Applies to: deferasirox
ADJUST DOSING INTERVAL: According to product labeling, the bioavailability of deferasirox was variably increased when taken with a meal.
MANAGEMENT: To ensure consistent plasma drug levels, deferasirox should be taken on an empty stomach 30 minutes before eating preferably at the same time everyday.
References
- (2005) "Product Information. Exjade (deferasirox)." Novartis Pharmaceuticals
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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