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Drug Interactions between Daranide and Trusopt

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

dichlorphenamide dorzolamide ophthalmic

Applies to: Daranide (dichlorphenamide) and Trusopt (dorzolamide ophthalmic)

GENERALLY AVOID: Following ophthalmic administration, brinzolamide and dorzolamide are systemically absorbed and may have additive pharmacologic effects with other, systemically administered carbonic anhydrase inhibitors. The risk of adverse effects such as drowsiness, paresthesia, tinnitus, electrolyte imbalance, metabolic acidosis, and gastrointestinal disturbances may be increased.

MANAGEMENT: The concomitant use of ocular and systemic carbonic anhydrase inhibitors is not recommended.

References

  1. "Product Information. Azopt (brinzolamide ophthalmic)." Alcon Laboratories Inc PROD (2001):
  2. "Product Information. Trusopt (dorzolamide ophthalmic)." Merck & Co., Inc PROD (2001):

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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