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Get key facts and figures about chronic dry eye

Drug interactions between Cosopt PF and Tustan 12S

Results for the following 2 drugs:
Cosopt PF (dorzolamide/timolol ophthalmic)
Tustan 12S (carbetapentane/chlorpheniramine)

Interactions between your drugs

Moderate

chlorpheniramine timolol ophthalmic

Applies to: Tustan 12S (carbetapentane / chlorpheniramine) and Cosopt PF (dorzolamide / timolol ophthalmic)

The medicine in timolol ophthalmic can be absorbed into the bloodstream, and using it with chlorpheniramine can further increase its levels in the blood. This may increase the risk of side effects such as breathing difficulties (especially if you have asthma or other respiratory diseases), depression, low blood pressure, and excessively slow heart rate. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

chlorpheniramine food

Applies to: Tustan 12S (carbetapentane / chlorpheniramine)

Alcohol can increase the nervous system side effects of chlorpheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with chlorpheniramine. Do not use more than the recommended dose of chlorpheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Moderate

carbetapentane food

Applies to: Tustan 12S (carbetapentane / chlorpheniramine)

Alcohol can increase the nervous system side effects of carbetapentane such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with carbetapentane. Do not use more than the recommended dose of carbetapentane, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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