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Drug Interactions between conjugated estrogens / medroxyprogesterone and Dexacort Phosphate in Respihaler

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

dexAMETHasone medroxyPROGESTERone

Applies to: Dexacort Phosphate in Respihaler (dexamethasone) and conjugated estrogens / medroxyprogesterone

DexAMETHasone may decrease the blood levels and effects of medroxyPROGESTERone. You may need a dose adjustment if you have been taking medroxyPROGESTERone and are starting treatment with dexAMETHasone. Contact your doctor if your condition changes during treatment with these medications. The interaction is not expected to occur if you are getting medroxyPROGESTERone by shot for birth control. However, let your doctor know if you experience bleeding outside of your menstrual cycle, since it may indicate reduced effectiveness of medroxyPROGESTERone. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

dexAMETHasone conjugated estrogens

Applies to: Dexacort Phosphate in Respihaler (dexamethasone) and conjugated estrogens / medroxyprogesterone

Conjugated estrogens may increase the blood levels of dexAMETHasone. This may increase the risk and/or severity of side effects such as swelling, weight gain, electrolyte abnormalities, high blood pressure, high blood glucose, muscle weakness, depression, mood swings, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, glaucoma, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Other side effects that may occur include decreased ability to fight infections, increased risk of developing infections, and inadequate response to stress such as infection, surgery, trauma, or a severe asthma attack. Children may experience a reduced growth rate during chronic use. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Minor

conjugated estrogens food

Applies to: conjugated estrogens / medroxyprogesterone

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.