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Drug interactions between Comtrex Allergy Sinus Maximum Strength and Quadrapax

Results for the following 2 drugs:
Comtrex Allergy Sinus Maximum Strength (acetaminophen/chlorpheniramine/pseudoephedrine)
Quadrapax (atropine/hyoscyamine/phenobarbital/scopolamine)

Interactions between your drugs

Moderate

chlorpheniramine scopolamine

Applies to: Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine) and Quadrapax (atropine / hyoscyamine / phenobarbital / scopolamine)

Using chlorpheniramine together with scopolamine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

chlorpheniramine hyoscyamine

Applies to: Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine) and Quadrapax (atropine / hyoscyamine / phenobarbital / scopolamine)

Using chlorpheniramine together with hyoscyamine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

chlorpheniramine PHENobarbital

Applies to: Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine) and Quadrapax (atropine / hyoscyamine / phenobarbital / scopolamine)

Using chlorpheniramine together with PHENobarbital may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

acetaminophen PHENobarbital

Applies to: Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine) and Quadrapax (atropine / hyoscyamine / phenobarbital / scopolamine)

Using acetaminophen together with PHENobarbital may alter the effects of acetaminophen and cause serious side effects that may affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

atropine chlorpheniramine

Applies to: Quadrapax (atropine / hyoscyamine / phenobarbital / scopolamine) and Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine)

Using atropine together with chlorpheniramine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

acetaminophen hyoscyamine

Applies to: Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine) and Quadrapax (atropine / hyoscyamine / phenobarbital / scopolamine)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Minor

acetaminophen scopolamine

Applies to: Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine) and Quadrapax (atropine / hyoscyamine / phenobarbital / scopolamine)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Minor

acetaminophen atropine

Applies to: Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine) and Quadrapax (atropine / hyoscyamine / phenobarbital / scopolamine)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Drug and food interactions

Moderate

chlorpheniramine food

Applies to: Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine)

Alcohol can increase the nervous system side effects of chlorpheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with chlorpheniramine. Do not use more than the recommended dose of chlorpheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Minor

scopolamine food

Applies to: Quadrapax (atropine / hyoscyamine / phenobarbital / scopolamine)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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