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Drug interactions between Comtrex Allergy Sinus Maximum Strength and Oraqix

Results for the following 2 drugs:
Comtrex Allergy Sinus Maximum Strength (acetaminophen/chlorpheniramine/pseudoephedrine)
Oraqix (lidocaine/prilocaine topical)

Interactions between your drugs

Major

acetaminophen prilocaine topical

Applies to: Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine) and Oraqix (lidocaine / prilocaine topical)

Talk to your doctor before using prilocaine topical together with acetaminophen. Prilocaine topical can cause a condition called methemoglobinemia that reduces the oxygen-carrying capacity of the blood to different organs, and combining the medication with acetaminophen may increase the risk. Infants and patients with certain conditions such as glucose-6-phosphate dehydrogenase deficiency or anemia are more likely to develop this condition. You should seek immediate medical attention if you notice signs and symptoms such as a gray discoloration of the skin, mouth, or nail bed; nausea; headache; dizziness; lightheadedness; fatigue; shortness of breath; rapid or shallow breathing; a rapid heartbeat; anxiety; and confusion. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

chlorpheniramine food

Applies to: Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine)

Alcohol can increase the nervous system side effects of chlorpheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with chlorpheniramine. Do not use more than the recommended dose of chlorpheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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