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Drug interactions between Rocaltrol and cholecalciferol

Results for the following 2 drugs:
Rocaltrol (calcitriol)
cholecalciferol

Interactions between your drugs

Major

calcitriol cholecalciferol

Applies to: Rocaltrol (calcitriol) and cholecalciferol

Using cholecalciferol together with calcitriol should generally be avoided unless otherwise directed by your doctor. Both of these medications are forms of vitamin D, and taking too much vitamin D can lead to toxic effects related to excessive calcium levels in the blood and urine, such as irregular heart rhythm, seizures, kidney stones, and eventual calcification of blood vessels, cornea, and soft tissues of the body. If you take digoxin, a common heart medication, having a high blood level of calcium can also increase the risk of developing digoxin toxicity. Talk to your doctor if you have any questions or concerns. You will need close monitoring of your calcium and phosphorus levels to safely use these medications. You should avoid an abrupt increase in your dietary calcium intake, and seek medical attention if you experience early symptoms of vitamin D intoxication such as weakness, fatigue, headache, drowsiness, vertigo, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Late symptoms may include frequent urination, excessive thirst, weight loss, conjunctivitis ("pink eye"), light sensitivity, runny nose, itching, increased body temperature, and irregular heart rhythm. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

No results found in our database - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Vitamin d analogs

Therapeutic duplication

The recommended maximum number of medicines in the 'vitamin d analogs' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'vitamin d analogs' category:

  • Rocaltrol (calcitriol)
  • cholecalciferol

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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