Drug interactions between cephalexin and Metro IV
|Metro IV (metronidazole)|
Interactions between your drugs
- Cephalexin is in the drug class first generation cephalosporins.
- Cephalexin is used to treat the following conditions:
A total of 363 drugs (1447 brand and generic names) are known to interact with Metro IV.
- Metro IV is a member of the following drug classes: amebicides, miscellaneous antibiotics.
- Metro IV is used to treat the following conditions:
- Aspiration Pneumonia
- Bacterial Infection
- Bacterial Vaginitis
- Balantidium coli
- Bone infection
- Clostridial Infection
- Crohn's Disease, Acute
- Crohn's Disease, Maintenance
- Deep Neck Infection
- Dental Abscess
- Dientamoeba fragilis
- Helicobacter Pylori Infection
- Intraabdominal Infection
- Joint Infection
- Lemierre's Syndrome
- Nongonococcal Urethritis
- Pelvic Inflammatory Disease
- Pseudomembranous Colitis
- Skin or Soft Tissue Infection
- STD Prophylaxis
- Surgical Prophylaxis
Drug and food interactions
Applies to: Metro IV (metronidazole)
Consumer information for this interaction is not currently available.
CONTRAINDICATED: Use of alcohol or products containing alcohol during nitroimidazole therapy may result in a disulfiram-like reaction in some patients. There have been a few case reports involving metronidazole, although data overall are not convincing. The presumed mechanism is inhibition of aldehyde dehydrogenase (ALDH) by metronidazole in a manner similar to disulfiram. Following ingestion of alcohol, inhibition of ALDH results in increased concentrations of acetaldehyde, the accumulation of which can produce an unpleasant physiologic response referred to as the 'disulfiram reaction'. Symptoms include flushing, throbbing in head and neck, throbbing headache, respiratory difficulty, nausea, vomiting, sweating, thirst, chest pain, palpitation, dyspnea, hyperventilation, tachycardia, hypotension, syncope, weakness, vertigo, blurred vision, and confusion. Severe reactions may result in respiratory depression, cardiovascular collapse, arrhythmia, myocardial infarction, acute congestive heart failure, unconsciousness, convulsions, and death. However, some investigators have questioned the disulfiram-like properties of metronidazole. One study found neither elevations in blood acetaldehyde nor objective or subjective signs of a disulfiram-like reaction to ethanol in six subjects treated with metronidazole (200 mg three times a day for 5 days) compared to six subjects who received placebo.
MANAGEMENT: Because clear evidence is lacking concerning the safety of ethanol use during nitroimidazole therapy, patients should be apprised of the potential for interaction. Consumption of alcoholic beverages and products containing propylene glycol is specifically contraindicated during and for at least 3 days after completion of metronidazole and benznidazole therapy according to their product labeling.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.