Sinemet CR Interactions
There are 520 drugs known to interact with Sinemet CR (carbidopa/levodopa), along with 13 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 50 are major, 459 are moderate, and 11 are minor.
- View all 520 medications that may interact with Sinemet CR
- View Sinemet CR alcohol/food interactions (1)
- View Sinemet CR disease interactions (13)
Most frequently checked interactions
View interaction reports for Sinemet CR (carbidopa / levodopa) and the medicines listed below.
- amantadine
- aspirin
- Aspirin Low Strength (aspirin)
- atorvastatin
- Azilect (rasagiline)
- baclofen
- clonazepam
- Comtan (entacapone)
- Cymbalta (duloxetine)
- Flomax (tamsulosin)
- gabapentin
- Lasix (furosemide)
- levothyroxine
- Lipitor (atorvastatin)
- lisinopril
- melatonin
- metformin
- MiraLAX (polyethylene glycol 3350)
- Mirapex (pramipexole)
- omeprazole
- pantoprazole
- Requip (ropinirole)
- ropinirole
- simvastatin
- Synthroid (levothyroxine)
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Zoloft (sertraline)
Sinemet CR alcohol/food interactions
There is 1 alcohol/food interaction with Sinemet CR (carbidopa / levodopa).
Sinemet CR disease interactions
There are 13 disease interactions with Sinemet CR (carbidopa / levodopa) which include:
- glaucoma
- cardiac disease
- neuroleptic malignant syndrome
- psychoses/depression
- glaucoma
- liver/renal
- melanoma
- reactive airway disease
- depression
- sleep disorders
- hypotension
- psychosis
- GI bleeding
Report options
More about Sinemet CR (carbidopa / levodopa)
- Sinemet CR consumer information
- Compare alternatives
- Reviews (4)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Drug class: dopaminergic antiparkinsonism agents
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
