Drug Interactions between Caltrate 600 with Iron and Vitamin D and Erleada
This report displays the potential drug interactions for the following 2 drugs:
- Caltrate 600 with Iron and Vitamin D (calcium/ferrous fumarate/vitamin d)
- Erleada (apalutamide)
Interactions between your drugs
calcium carbonate ferrous fumarate
Applies to: Caltrate 600 with Iron and Vitamin D (calcium / ferrous fumarate / vitamin d) and Caltrate 600 with Iron and Vitamin D (calcium / ferrous fumarate / vitamin d)
By reducing the acidity level in the stomach, medications like calcium carbonate may interfere with the absorption of ferrous fumarate into the bloodstream and reduce its effectiveness. If you require treatment with both medications, it is recommended that you take ferrous fumarate at least 2 hours before or 2 hours after calcium carbonate to help minimize the impact of the interaction. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
cholecalciferol apalutamide
Applies to: Caltrate 600 with Iron and Vitamin D (calcium / ferrous fumarate / vitamin d) and Erleada (apalutamide)
Consumer information for this interaction is not currently available.
MONITOR: Coadministration with CYP450 inducers such as rifampin, isoniazid, barbiturates, and certain anticonvulsants may decrease the pharmacologic effects of vitamin D analogs. These agents are thought to induce the hepatic conversion of vitamin D to inactive metabolites and have been shown to reduce circulating levels of active vitamin D, sometimes accompanied by reduced serum calcium and increased parathyroid hormone levels. Patients on long-term anticonvulsant therapy have occasionally developed osteomalacia, presumably due to interference with vitamin D and calcium metabolism. There have also been isolated reports of patients who responded poorly to vitamin D supplements during treatment with phenytoin and/or primidone.
MANAGEMENT: Patients receiving vitamin D analogs with CYP450 inducers should be monitored for potentially reduced vitamin D effects. Dosage adjustments may be necessary.
Drug and food interactions
calcium carbonate food
Applies to: Caltrate 600 with Iron and Vitamin D (calcium / ferrous fumarate / vitamin d)
Calcium absorption may be increased by taking it with food. However, foods high in oxalic acid (spinach or rhubarb), or phytic acid (bran and whole grains) may decrease calcium absorption. Calcium may be taken with food to increase absorption. Consider spacing calcium administration for at least 2 hours before or after consuming foods high in oxalic acid or phytic acid. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ferrous fumarate food
Applies to: Caltrate 600 with Iron and Vitamin D (calcium / ferrous fumarate / vitamin d)
Food may reduce the absorption and blood levels of ferrous fumarate. In addition, some oral medications can also interfere with ferrous fumarate absorption into the bloodstream, which may make the medication less effective in treating your condition. Likewise, ferrous fumarate may interfere with the absorption of other orally administered medications. You should take ferrous fumarate on an empty stomach at least one hour before or two hours after a meal. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Talk to your doctor or pharmacist if you have questions about how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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