Skip to Content

Butrans (buprenorphine) Drug Interactions

A total of 1101 drugs are known to interact with Butrans (buprenorphine).

  • 321 major drug interactions
  • 770 moderate drug interactions
  • 10 minor drug interactions

Show all medications in the database that may interact with Butrans (buprenorphine).

Check for interactions with Butrans (buprenorphine)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Butrans (buprenorphine)

  • Adderall (amphetamine / dextroamphetamine)
  • amitriptyline (Elavil, Endep, Vanatrip)
  • atorvastatin (Lipitor)
  • baclofen (Lioresal, Gablofen, Kemstro, Lioresal Intrathecal)
  • clonazepam (Klonopin, Klonopin Wafer)
  • codeine
  • cyclobenzaprine (Flexeril, Amrix, Fexmid, Comfort Pac with Cyclobenzaprine)
  • Cymbalta (duloxetine)
  • diazepam (Valium, Diastat, Diazepam Intensol, Diastat AcuDial, Zetran, Diastat Pediatric, Dizac, Valrelease)
  • fentanyl (Duragesic, Fentanyl Transdermal System, Actiq, Sublimaze, Abstral, Lazanda, Fentora, Subsys, Ionsys, Onsolis)
  • Flexeril (cyclobenzaprine)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • hydrocodone (Hysingla ER, Zohydro ER, Vantrela ER)
  • ibuprofen (Advil, Motrin, IBU, Proprinal, Advil Liqui-Gels, Motrin IB, IBU-200, Nuprin, Children's Motrin, Motrin Migraine Pain, Advil Migraine, Caldolor, Ibuprofen PMR, Advil Children's, Addaprin, NeoProfen, Advil Infant's Concentrated Drops, A-G Profen, Motrin Childrens, Childrens Ibuprofen Berry, Ibu-6, Ibu-8, Motrin Infant Drops, Ibu-Tab, Rufen, Genpril, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • Klonopin (clonazepam)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Unithroid, Levothyrox, Euthyrox, Levo-T, L Thyroxine Roche, Eutroxsig, Novothyrox, Oroxine, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • Lyrica (pregabalin)
  • metformin (Glucophage, Glumetza, Glucophage XR, Riomet, Fortamet)
  • morphine (MS Contin, Morphine Sulfate ER, Roxanol, Morphine Sulfate IR, Kadian, MSIR, MorphaBond ER, Morphine Sulfate SR, Duramorph, Avinza, Morphine LP Epidural, Oramorph SR, Arymo ER, Statex, Astramorph PF, Mitigo, Morphine Rapi-Ject, Roxanol-T, RMS, Infumorph, Duramorph PF, OMS, Roxanol 100, Rescudose, MS/S, Doloral, Doloral Sirop, M-Eslon, Morphitec, M O S)
  • Norco (acetaminophen / hydrocodone)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Percolone, Oxyfast, Dazidox, RoxyBond, Oxecta, Oxydose, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol)
  • Paracetamol (acetaminophen)
  • Percocet (acetaminophen / oxycodone)
  • Suboxone (buprenorphine / naloxone)
  • tizanidine (Zanaflex)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Tramedo, Ultram ER, Larapam SR, GenRx Tramadol, ConZip, Zydol, Ryzolt, Tramahexal, Zamadol, Tramal SR, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Tylenol (acetaminophen)
  • Valium (diazepam)
  • Vicodin (acetaminophen / hydrocodone)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)

Butrans (buprenorphine) alcohol/food interactions

There is 1 alcohol/food interaction with Butrans (buprenorphine)

Butrans (buprenorphine) disease interactions

There are 14 disease interactions with Butrans (buprenorphine) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide