Drug Interactions between budesonide / formoterol and Nydrazid
This report displays the potential drug interactions for the following 2 drugs:
- budesonide/formoterol
- Nydrazid (isoniazid)
Interactions between your drugs
isoniazid budesonide
Applies to: Nydrazid (isoniazid) and budesonide / formoterol
Isoniazid may increase the absorption of the medication from budesonide into the blood stream. In some cases, this can increase side effects such as swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Other side effects that may occur include decreased ability to fight infections, increased risk of developing infections, and inadequate response to stress such as infection, surgery, trauma, or a severe asthma attack. Children may experience a reduced growth rate due to excessive effects of budesonide. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
isoniazid formoterol
Applies to: Nydrazid (isoniazid) and budesonide / formoterol
Consumer information for this interaction is not currently available.
MONITOR: Monoamine oxidase inhibitors (MAOIs) can potentiate the cardiovascular adverse effects of beta-2 adrenergic agonists such as hypertension, palpitation, tachycardia, and chest pain.
MANAGEMENT: Cardiovascular status should be closely monitored when beta-2 agonists are coadministered with MAOIs or other agents that possess MAOI activity (e.g., furazolidone, linezolid, methylene blue, procarbazine). Preferably, at least 14 days should elapse between discontinuation of MAOI therapy and initiation of treatment with beta-2 agonists.
References
- Finch JS "Cardiovascular toxicity: clinical evaluation of albuterol, isoproterenol and placebo in rising dose tolerance trial." Ann Allergy 47 (1981): 402-4
- "Adverse effects and complications of treatment with beta-adrenergic agonist drugs. Committee on drugs, the American Academy of Allergy and Immunology." J Allergy Clin Immunol 75 (1985): 443-9
- "Product Information. Proventil (albuterol)." Schering Corporation PROD (2002):
- "Product Information. Brethaire (terbutaline)." Novartis Pharmaceuticals PROD (2001):
- "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals PROD (2001):
- "Product Information. Serevent (salmeterol)." Glaxo Wellcome PROD
- "Product Information. Maxair (pirbuterol)." 3M Pharmaceuticals PROD (2001):
- Boakes AJ, Laurence DR, Teoh PC, Barar FS, Benedikter LT, Prichard BN "Interactions between sympathomimetic amines and antidepressant agents in man." Br Med J 1 (1973): 311-5
- Darcy PF, Griffin JP "Interactions with drugs used in the treatment of depressive illness." Adverse Drug React Toxicol Rev 14 (1995): 211-31
- "Product Information. Alupent (metaproterenol)." Boehringer-Ingelheim PROD (2001):
- "Product Information. Tornalate (bitolterol)." Apothecon Inc (2022):
- "Product Information. Xopenex (levalbuterol)." Sepracor Inc PROD (2001):
- "Product Information. Foradil (formoterol)." Novartis Pharmaceuticals PROD (2001):
- "Product Information. Brovana (arformoterol)." Sepracor Inc (2006):
- "Product Information. S2 Inhalant (racepinephrine)." Nephron Pharmaceuticals (2010):
- "Product Information. Arcapta Neohaler (indacaterol)." Novartis Pharmaceuticals (2011):
- "Product Information. Breo Ellipta (fluticasone-vilanterol)." GlaxoSmithKline (2013):
- "Product Information. Striverdi Respimat (olodaterol)." Boehringer Ingelheim (2014):
budesonide formoterol
Applies to: budesonide / formoterol and budesonide / formoterol
Information for this minor interaction is available on the professional version.
Drug and food interactions
isoniazid food
Applies to: Nydrazid (isoniazid)
Food decreases the levels of isoniazid in your body. Take isoniazid on an empty stomach at least 1 hour before or 2 hours after a meal. This will make it easier for your body to absorb the medication. If nausea occurs, ask your doctor if you can take isoniazid with food. Avoid alcohol while taking isoniazid. Alcohol may increase the risk of damage to the liver during isoniazid treatment. Alcohol can also cause isoniazid side effects to get worse. Contact your doctor if you experience flushing, chills, headache, nausea, vomiting, and diarrhea.
budesonide food
Applies to: budesonide / formoterol
You should avoid the regular consumption of large amounts of grapefruits and grapefruit juice while taking budesonide. Grapefruit can raise the levels of budesonide in your body and lead to increased side effects. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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