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Drug Interactions between Biktarvy and Focalgin-B

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

calcium phosphate, tribasic bictegravir

Applies to: Focalgin-B (calcium / folic acid / ginger / pyridoxine) and Biktarvy (bictegravir / emtricitabine / tenofovir alafenamide)

Products that contain aluminum, calcium, iron, magnesium or other minerals such as antacids and supplements may interfere with the absorption of bictegravir and reduce its effectiveness in treating HIV infection. Additionally, it may lead to development of viral resistance to this and various other HIV medications that are currently used for treatment. When used with antacids, you should generally take bictegravir on an empty stomach at least two hours before the antacid. Avoid taking bictegravir simultaneously with, or 2 hours after, antacid dosing whenever possible. When used with multivitamin or mineral supplements, you may take bictegravir and supplements together at the same time, but with food. Avoid taking bictegravir on an empty stomach simultaneously with, or 2 hours after, dosing of supplements. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

folic acid food

Applies to: Focalgin-B (calcium / folic acid / ginger / pyridoxine)

Talk to your doctor before using alcohol together with folic acid. Excessive consumption of alcohol may reduce the absorption and increase the elimination of folic acid. Contact your doctor if your symptoms worsen or your condition changes. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

calcium phosphate, tribasic food

Applies to: Focalgin-B (calcium / folic acid / ginger / pyridoxine)

Calcium absorption may be increased by taking it with food. However, foods high in oxalic acid (spinach or rhubarb), or phytic acid (bran and whole grains) may decrease calcium absorption. Calcium may be taken with food to increase absorption. Consider spacing calcium administration for at least 2 hours before or after consuming foods high in oxalic acid or phytic acid. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

tenofovir food

Applies to: Biktarvy (bictegravir / emtricitabine / tenofovir alafenamide)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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