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Drug Interactions between Bevespi Aerosphere and Timolide

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

timolol formoterol

Applies to: Timolide (hydrochlorothiazide / timolol) and Bevespi Aerosphere (formoterol / glycopyrrolate)

Using timolol together with formoterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, timolol can sometimes cause narrowing of the airways, which may worsen your breathing problems or trigger severe asthmatic attacks. Timolol is normally not recommended if you have asthma, a history of asthma, or severe chronic obstructive pulmonary disease (COPD). Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact or are less likely to interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

timolol hydroCHLOROthiazide

Applies to: Timolide (hydrochlorothiazide / timolol) and Timolide (hydrochlorothiazide / timolol)

Using timolol and hydroCHLOROthiazide together may lower your blood pressure and slow your heart rate. This can cause dizziness, or feeling like you might pass out, weakness, fainting, fast or irregular heartbeats, or loss of blood glucose control. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or need your blood pressure checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

timolol glycopyrrolate

Applies to: Timolide (hydrochlorothiazide / timolol) and Bevespi Aerosphere (formoterol / glycopyrrolate)

Using glycopyrrolate together with timolol may alter the effects of both medications. Contact your doctor if you experience drowsiness, dizziness, lightheadedness, confusion, blurred vision, dry mouth, or difficulty urinating. You may need a dose adjustment or need your blood pressure checked more often to safely use both medications. You should avoid activities requiring mental alertness until you know how the medications will affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

hydroCHLOROthiazide formoterol

Applies to: Timolide (hydrochlorothiazide / timolol) and Bevespi Aerosphere (formoterol / glycopyrrolate)

Using hydroCHLOROthiazide together with formoterol may increase the risk of developing hypokalemia, or low blood potassium. In severe cases, hypokalemia can lead to muscle weakness, paralysis, breathing and swallowing difficulties (due to muscle paralysis), and irregular heart rhythm. The risk may exist even when formoterol or similar medications are given by oral inhalation directly into the lungs, and more so if these products are overused. Do not exceed the dose and frequency of use recommended on the product label or prescribed by your doctor. Let your doctor know if you experience nausea, vomiting, constipation, abdominal cramping, confusion, dizziness, lightheadedness, fainting, muscle weakness, muscle cramps, numbness, tingling, rapid heartbeat, chest pain, and/or swelling in the legs or feet, as these may be symptoms of hypokalemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

hydroCHLOROthiazide glycopyrrolate

Applies to: Timolide (hydrochlorothiazide / timolol) and Bevespi Aerosphere (formoterol / glycopyrrolate)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

timolol food

Applies to: Timolide (hydrochlorothiazide / timolol)

Timolol and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

hydroCHLOROthiazide food

Applies to: Timolide (hydrochlorothiazide / timolol)

HydroCHLOROthiazide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

glycopyrrolate food

Applies to: Bevespi Aerosphere (formoterol / glycopyrrolate)

Ask your doctor before using glycopyrrolate together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking glycopyrrolate. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

timolol food

Applies to: Timolide (hydrochlorothiazide / timolol)

Using timolol together with multivitamin with minerals may decrease the effects of timolol. Separate the administration times of timolol and multivitamin with minerals by at least 2 hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.