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Drug interactions between bcg and mitomycin

Results for the following 2 drugs:
bcg
mitomycin

Interactions between your drugs

Major

mitoMYcin BCG

Applies to: mitomycin and bcg

Consumer information for this interaction is not currently available.

CONTRAINDICATED: Administration of intravesicular BCG in patients receiving immunosuppressants, bone marrow depressants, and/or antineoplastic therapy may be associated with an increased risk of disseminated BCG infection. In addition, these patients may not develop an adequate immune response which would reduce the anti-tumor efficacy of BCG. Patients may be immunosuppressed if they have recently received or are receiving alkylating agents, antimetabolites, radiation, some antirheumatic agents, high dosages of corticosteroids or adrenocorticotropic agents (e.g., greater than 10 mg/day or 1 mg/kg/day of prednisone or equivalent for more than 2 weeks), or long-term topical or inhaled corticosteroids.

MANAGEMENT: Use of intravesicular BCG in immunosuppressed patients is considered contraindicated.

References

  1. Cerner Multum, Inc. "Australian Product Information." O 0
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. "Product Information. Tice BCG Vaccine (BCG (BCG vaccine))." Organon, West Orange, NJ.

Drug and food interactions

No results found in our database - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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