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Drug Interactions between atropine / edrophonium and hydrochlorothiazide / quinapril

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

atropine edrophonium

Applies to: atropine / edrophonium and atropine / edrophonium

Ask your doctor before using edrophonium together with atropine. Using these medications together can cause increasing muscle weakness. In addition, such use may mask the less serious, gastrointestinal signs of atropine overdose and lead to difficulty breathing, chest pain, and possibly death. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

atropine quinapril

Applies to: atropine / edrophonium and hydrochlorothiazide / quinapril

Quinapril can bind to atropine in the gastrointestinal tract. This may inactivate atropine or interfere with its absorption into the bloodstream, possibly reducing its effectiveness. To avoid or minimize the interaction, you should try to take them at least 2 to 3 hours apart. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

hydroCHLOROthiazide quinapril

Applies to: hydrochlorothiazide / quinapril and hydrochlorothiazide / quinapril

Although hydroCHLOROthiazide and quinapril are frequently combined together, their effects may be additive on lowering your blood pressure. You may need a dose adjustment or special tests to safely take both medications. Contact your doctor if you have a reduced heart rate, dizziness, fainting, or headaches. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

atropine hydroCHLOROthiazide

Applies to: atropine / edrophonium and hydrochlorothiazide / quinapril

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

quinapril food

Applies to: hydrochlorothiazide / quinapril

It is recommended that if you are taking quinapril you should be advised to avoid moderately high or high potassium dietary intake. This can cause high levels of potassium in your blood. Do not use salt substitutes or potassium supplements while taking quinapril, unless your doctor has told you to.

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Moderate

atropine food

Applies to: atropine / edrophonium

Ask your doctor before using atropine together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking atropine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

hydroCHLOROthiazide food

Applies to: hydrochlorothiazide / quinapril

HydroCHLOROthiazide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

quinapril food

Applies to: hydrochlorothiazide / quinapril

Quinapril and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.