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Drug Interactions between atazanavir / cobicistat and Depo Provera

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

medroxyPROGESTERone atazanavir

Applies to: Depo Provera (medroxyprogesterone) and atazanavir / cobicistat

Ask your doctor before using medroxyPROGESTERone together with atazanavir. Atazanavir may affect the safety and decrease the birth control effectiveness of medroxyPROGESTERone. Women who use birth control pills or birth control patches should choose a different kind of contraception during atazanavir therapy. Using medroxyPROGESTERone together with atazanavir can also increase the blood levels or add to the side effects of medroxyPROGESTERone. This can cause sudden headache, confusion, pain behind the eyes, problems with vision, speech, or balance, nausea, and stomach pain. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

medroxyPROGESTERone cobicistat

Applies to: Depo Provera (medroxyprogesterone) and atazanavir / cobicistat

Talk to your doctor before using cobicistat together with medroxyPROGESTERone. Combining these medications may alter the effects of some hormone-based medications. Birth control pills and hormone replacement therapy may become less effective. Also, the risk of side effects such as insulin resistance, lipid disorders, acne, and blood clots may increase. Talk to your gynecologist or other healthcare professional for help in selecting effective methods of birth control that work best for you. If you take hormone replacement for menopause, you should contact your doctor if you experience increased frequency or worsening of your symptoms such as hot flashes, vaginal dryness, or abnormal bleeding. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

atazanavir food

Applies to: atazanavir / cobicistat

Food can enhance the levels of atazanavir in your body. To ensure maximal oral absorption, atazanavir should be administered with or immediately after a meal. This will make it easier for your body to absorb the medication.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.