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Bufferin (aspirin) Drug Interactions

A total of 504 drugs are known to interact with Bufferin (aspirin).

  • 78 major drug interactions
  • 352 moderate drug interactions
  • 74 minor drug interactions

Show all medications in the database that may interact with Bufferin (aspirin).

Check for interactions with Bufferin (aspirin)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Bufferin (aspirin)

  • Anacin (aspirin / caffeine)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Aspir-Low, Bayer Aspirin, Ecotrin Adult Low Strength, Ascriptin, Fasprin, Arthritis Pain, Low Dose ASA, Aspiritab, Bufferin, Durlaza, Aspirin Lite Coat, Aspirtab, Halfprin, Bayer Children's Aspirin, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Easprin, Aspergum, Buffered Aspirin, Ascriptin Enteric, Acuprin 81, Miniprin, Bayer Aspirin Regimen, St. Joseph 81 mg Chewable Aspirin, Empirin, Ecotrin Maximum Strength, St. Joseph Aspirin, Ecpirin, Bayer Women's Aspirin With Calcium, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspi-Cor, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Bayer Aspirin Extra Strength Plus, Buffex, Entercote, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Zero-Order Release, YSP Aspirin, Migralex, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Centrum Silver (multivitamin with minerals)
  • cholecalciferol (Vitamin D3, D3, Decara, Replesta, Celebrate Vitamin D3 Quick-Melt, Maximum D3, D2000, D 1000 IU, Thera-D 2000, Delta D3, Ddrops, D-Vita Drops, Replesta Children's, Replesta NX, Thera-D 4000, Carlson D, Bio-D-Mulsion, Bio-D-Mulsion Forte, Enfamil D-Vi-Sol, BProtected Pedia D-Vite, Thera-D Rapid Repletion, D400, D3-5, D3-50, UpSpringbaby D, Wellesse Vitamin D3)
  • Claritin (loratadine)
  • Crestor (rosuvastatin)
  • digoxin (Lanoxin, Digox, Digitek, Lanoxicaps, Cardoxin)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • furosemide (Lasix, Diaqua-2, Lo-Aqua)
  • heparin (Heparin Sodium)
  • hydrochlorothiazide (HydroDIURIL, Microzide, Esidrix, Oretic, Diaqua, Aquazide H, Hydro Par, Ezide, Carozide, Loqua)
  • ibuprofen (Advil, Motrin, IBU, Proprinal, Advil Liqui-Gels, Motrin IB, IBU-200, Nuprin, Children's Motrin, Motrin Migraine Pain, Advil Migraine, Caldolor, Ibuprofen PMR, Advil Children's, Addaprin, NeoProfen, Advil Infant's Concentrated Drops, A-G Profen, Motrin Childrens, Childrens Ibuprofen Berry, Ibu-6, Ibu-8, Motrin Infant Drops, Ibu-Tab, Rufen, Genpril, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Unithroid, Levothyrox, Euthyrox, Levo-T, L Thyroxine Roche, Eutroxsig, Novothyrox, Oroxine, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • loratadine (Claritin, Alavert, Allergy Relief Tablets, Claritin 24 Hour Allergy, Claritin Reditabs, Loratadine Reditab, Wal-itin, Help I Have Allergies, Children's Claritin Allergy, Allergy Relief 24 Hour, Children's Allergy Relief 24 Hour, Vicks QlearQuil All Day & All Night 24 Hour Allergy Relief, ohm Allergy Relief, Clear-Atadine, Claritin Hives Relief, Dimetapp Children's ND Non-Drowsy Allergy, Clear-Atadine Children's, Bactimicina Allergy, Tavist ND)
  • losartan (Cozaar)
  • metformin (Glucophage, Glumetza, Glucophage XR, Riomet, Fortamet)
  • multivitamin with minerals (Ocuvite, Centrum Silver, Centrum, PreserVision, PreserVision AREDS 2, Calcium 600+D Plus Minerals, Certa-Vite Senior Plus Lutein, Emergen-C, Airborne, Theragran-M, Folgard, Calcium Magnesium Potassium, ICaps AREDS, Antioxid Caplets, Viactiv Calcium Flavor Glides, AquADEKs, Antioxidant Formula, Ocuvite Lutein, ProRenal QD, Strovite, MultiVitamin Plus Zinc, Hemocyte Plus, Certa-Vite, Centrum Silver Men's, I-Vite, Flintstones Complete, Nicotinamide ZCF, Viactiv Multi-Vitamin, RenaPlex, Centrum Silver Women's, Centrum Adults, TheraLith XR, Cerovite Senior, Dolomite, Caltrate Plus, Prosteon, Certavite, Vitafol, Ocuvite Extra, Daily Multi-Vitamins with Minerals, Nicaprin, Hemax, Lipoflavovit, AquADEKs Pediatric, Therems M, Central-Vite, Cerovite Advanced Formula, Vitamin C plus Zinc, Thera-M, Prosight with Lutein, Geritol Complete, Nicadan, MagneBind 400 Rx, Ellis Tonic Sherry, ProRenal Vital, Caltrate 600 Plus, Spectravite Senior, Tozal, Support 500, Centamin, Bacmin, Advanced AM/PM, Celebrate Calcium Plus 500, Prosight, Strovite One, Theragener-M, Macular Vitamin Benefit, SSS, Eldertonic, ICaps with Lutein and Zeaxan, Viactiv Soft Calcium Chews, Certagen Senior with Lutein, ProCerv HP, Renax, Ocuvite PreserVision, Centavite, Siderol, MaxFe, Caltrate 600+D Plus Minerals, Renax 5.5, Ocuvite Eye + Multi, Stress with Zinc, Centrum Silver Ultra Men's, PureVit DualFe Plus, Senetonic, Airborne Plus Energy, Becomax Rx, StressTabs with Zinc, Vital-D, Vitatab MV, Centrum Flavor Burst, Centratex, NanoVM, Macular Health Formula, Central, Apetigen-Plus, 50 + Companion, Womens Pack, Supervite, Mens Pack, Citracal Plus Bone Density Builder, Dialyvite Supreme D, Vol-Plus, Daily Multiple for Men 50+, Multilex-T/M+Minerals, Vicon-C, Gynovite, Actiflovit, Spectravite Cardio Health, Calcium, Magnesium and Zinc, Myvitalife, Vitamax, Centrum Specialist Vision, Theravim M, Beelith, elppa Daily, Citracal Plus Magnesium, Conception XR, Embrex 600, CertaVite with Antioxidants, Nicomide, Tab-A-Vite Maximum, Folgard OS, NicAzel, Optisource Post Bariatric Surgery, Somnicin, Abatron, Tandem Plus, Multi-Day Plus Minerals, CertaVite Senior, ABC Plus Senior, I-Vite Protect, Daily-Vite Weight Control, Biotin Forte with Zinc, Healthy Eyes, elon Matrix 5000 Complete, Centrum Vitamints, Berocca Plus, PureFe Plus, Vicon Forte, Vitatrum, Daily Multi, Magna-C-7 Forte, Macular Health, Zincvit, Centravites 50 Plus, Vica-Forte, V-C Forte, Cezin-S, AKEDamins, Eldercaps, Corvita 150, Solo, Vitacon Forte, Caromega, Vita-Min Rx, Advanced Eye Health, Airborne Dual Action, Circavite T, Airborne Everyday, Vitalize Plus, TL G-Fol OS, Airborne Everyday Gummies, Therobec Plus, Airborne Gummies, Zodeac-100, Airborne Kids Gummies, Vitaplex Plus, Berplex Plus, Strovite Plus, Betamed, Vicon Plus, Optilets-M-500, Se-Tan Plus, Fosfree, Surbex-750 with Zinc, SourceCF Multivitamins with A,B,D,E & K plus Zinc, Alka-Seltzer Plus Immunity Complex, SourceCF Softgels, SourceCF Chewables, Recal D, ChoiceFul, SourceCF Pediatric Drops, Rx Support Heartburn and Acid Reflux, CalMag Thins, Zinc Plus Lozenges, Centrum Special Immune, Gevrabon, Sesame St Vitamins Complete, Dialyvite 5000, Century, One-A-Day Within, One-A-Day Men Pro Edge, One-A-Day Vitacraves, Celebrate Multivitamin, Certagen, ProBarimin QT, B-Plex Plus Minerals, Multigenics, Optivite PMT, Bugs Bunny Complete, ICaps Plus, Risanoid Plus, ABC to Z, One Tab Daily with Minerals, Bladder 2.2, Diavite Plus, Centrum Special Energy, Centrum Special Heart, One Daily with Minerals, Companion Multi, One-A-Day Max, ConceptionXR MSF, ConceptionXR RHF, Essentia, Complete Formulation Minis, Century-Vite, Genicin Vita-Q, One-A-Day Women, Genicin Vita-S, Caltrate 600+D Plus Minerals Minis, Calcet Plus, Gerivite Liquid, Lysiplex Plus, Generix-T, NanoVM 1-3 years, Certagen Senior, NanoVM 4-8 years, Decagen, Geri-Tonic, Avail Calcium Intensive, Vita-Dec, Multilex, Vigortol Liquid, Centrum Silver Plus Vision, Cerovite Liquid, Myadec, Req49+, Multi-Day with Calcium and Extra Iron, Flintstones with Calcium, Supervite EC, Thyrosol, Magonate Tablets, Therapeutic-M, T-Lite, Unicap M, Gevratonic, Gold Age Liquid Vitamins and Minerals, Unicap Senior, Garfield Complete Vitamins, Z-Bec, Complete Formulation Chewables D3000, Z-Gen, Daily Multiple for Women, Complete Formulation Pediatric Drops, Hair Booster, Daily Multiple for Women 50+, Complete Formulation Softgels D3000, Complete Formulation Softgels D5000, Eye Health Formula, TheraCal D2000, Unicap T, TheraCal D4000, TheraCal Rapid Repletion, Viogen-C, PMS Balance, Procycle Multi Vitamin with Minerals, Dialyvite 800 Ultra D, VP-ZEL, Adeks, Stress 600 with Zinc, Leg-Gesic, Stress Formula with Zinc, Theragener-H, Vi-Zac, Centrum Cardio, Vita-Zinc, Renatabs with Iron, RenaPlex-D, Complete Formulation Chewables, Uni-Thera M with Beta Carotene, CertaVite with Lutein, T-Gran plus Minerals, My-A-Multi, Century Senior, Cerovite Junior, Bee-Zee, Compete, Formula Twenty-One, Mi-C-T, I-Fol Plus, Thera Hematinic, Flintstones Gummies, ABDEK, I-Sense, Foli-Iron, ABDEK Pediatric, Nicadan ZX, Complete Formulation, Unicomplex M, Complete Formulation D3000, Ru-Lets M 500, Complete Formulation D5000, Apatate Forte, Corvita, Nu-Iron V, SourceCF ABDEK, L'il Critters Gummy Vites, Daily Combo, Super High Vitamins and Minerals, Corvite Free, Icaps TR, Corvite 150, RE Fac-X, Geritol Extend, Theratrum Complete 50 Plus with Lutein and Lycopene, Companion, Theratrum Complete with Lutein and Lycopene, Complete Formulation Softgels, Strovite Forte, ZE-Plus, Glutofac-ZX, MaxiVision Eye & Body Formula, Reocyte Plus, MaxiVision Eye Formula, DermaNIC, L-Tonic, Re Dualvit F, MaxiVision Ocular Formula, DermaVite, Re Dualvit Plus, Glutofac-MX, MaxiVision Whole Body Formula, Nature's Bounty Men's Hair Formula, Mediplex Ultra, Nutiifac ZX, NicAzel Forte, Formula B Plus, Hematinic Plus, M-Vit, Support, Vicap Forte, Vita S Forte, Centrum Performance, Protegra Softgel, Strovite Advance, Centravites Adults, I-Sense OccuShield, Occuplex, Uni-Fac ZX, Dialyvite with Zinc Rx, Dialyvite 800 with Zinc, CF Vite, Strovite Advance+D, Resource Optisource, High Potency, Tab-A-Vite Womens Formula, Astamed MYO, Tab-A-Vite WeightSlim, DEKAs Plus, Dialyvite 3000, Udamin, Udamin SP, Vita Zx, CalciFol, Femtabs, Diatx Zn, Complete A-Z, Thera-Vite M, Nutravance, O-CAL FA, ICaps MV, Men's Hair Formula, Nature's Blend Theratrum Complete Tablets 50 Plus, One-A-Day Mens 50+ Healthy Advantage, Os-Cal Ultra, Puralor Ci with DHA, Opti-Gen, Encora, Star Wars, Disney Winnie the Pooh Complete, Nutricap, Star Wars Hero Gummies, Disney Winnie the Pooh with Extra C, Nutrivit, Star Wars Villain Gummies, Disney Winnie the Pooh Gummies, Star Wars Yoda Gummies, Mag-SR with Calcium, Folpace Rx, Calafol Rx, Corvite, NIC 750, CalciFolic-D, Ostiva, One-A-Day WeightSmart, Ferrocite Plus, Centrum Kids, Ecee Plus, Viactiv Multi-Vitamin Flavor Glides, Folbee Plus CZ, Antioxidant Ultra Formula, Centrum Ultra Men's, Clusimar, Multi-betic, Centrum Silver Ultra Women's, Centrum Ultra Women's, One-A-Day Women 50 Plus, One-A-Day Men 50 Plus, Thera-M Enhanced, Megavite Rx, Centrum Jr with Extra Calcium, ICaps Lutein & Omega-3, Centrum MultiGummies Women, Recal Fol D)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • pravastatin (Pravachol)
  • sulfamethoxazole / trimethoprim (Bactrim, Bactrim DS, Septra, SMZ-TMP DS, Septra DS, Co-trimoxazole, Sulfatrim, Bactrim Pediatric, Sulfatrim Pediatric, Cotrim, Bethaprim, Uroplus, Uroplus DS, Cotrim DS, Septra IV, Bactrim IV, Bethaprim Pediatric, Cotrim Pediatric)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Tramedo, Ultram ER, Larapam SR, GenRx Tramadol, ConZip, Zydol, Ryzolt, Tramahexal, Zamadol, Tramal SR, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
  • Vitamin C (ascorbic acid)
  • Vitamin D3 (cholecalciferol)

Bufferin (aspirin) alcohol/food interactions

There are 2 alcohol/food interactions with Bufferin (aspirin)

Bufferin (aspirin) disease interactions

There are 9 disease interactions with Bufferin (aspirin) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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