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Drug Interactions between Aralen and Complete Acid Reducer plus Antacid

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

chloroquine famotidine

Applies to: Aralen (chloroquine) and Complete Acid Reducer plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Using famotidine together with chloroquine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances (for example, magnesium or potassium loss due to severe or prolonged diarrhea or vomiting). Talk to your doctor if you have any questions or concerns. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications, whether together or alone. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

chloroquine calcium carbonate

Applies to: Aralen (chloroquine) and Complete Acid Reducer plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

It is best not to take chloroquine and calcium carbonate at the same time. Products that contain magnesium, aluminum, or calcium such as antacids and some other gastrointestinal medications may interfere with the absorption of chloroquine and reduce its effectiveness. To minimize the risk of an interaction, you should try to separate the dosing of these medications by at least 4 hours. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

chloroquine magnesium hydroxide

Applies to: Aralen (chloroquine) and Complete Acid Reducer plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

It is best not to take chloroquine and magnesium hydroxide at the same time. Products that contain magnesium, aluminum, or calcium such as antacids and some other gastrointestinal medications may interfere with the absorption of chloroquine and reduce its effectiveness. To minimize the risk of an interaction, you should try to separate the dosing of these medications by at least 4 hours. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

famotidine calcium carbonate

Applies to: Complete Acid Reducer plus Antacid (calcium carbonate / famotidine / magnesium hydroxide) and Complete Acid Reducer plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Information for this minor interaction is available on the professional version.

Minor

famotidine magnesium hydroxide

Applies to: Complete Acid Reducer plus Antacid (calcium carbonate / famotidine / magnesium hydroxide) and Complete Acid Reducer plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

chloroquine food

Applies to: Aralen (chloroquine)

You may want to limit your consumption of grapefruit or grapefruit juice during treatment with chloroquine. Grapefruit juice can significantly increase the blood levels and effects of chloroquine, which may result in an irregular heart rate or other conduction disturbances. Talk to your doctor if you have any questions or concerns. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with chloroquine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

calcium carbonate food

Applies to: Complete Acid Reducer plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Calcium absorption may be increased by taking it with food. However, foods high in oxalic acid (spinach or rhubarb), or phytic acid (bran and whole grains) may decrease calcium absorption. Calcium may be taken with food to increase absorption. Consider spacing calcium administration for at least 2 hours before or after consuming foods high in oxalic acid or phytic acid. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

famotidine food

Applies to: Complete Acid Reducer plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.