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Drug Interactions between amoxicillin / clarithromycin / lansoprazole and atazanavir / cobicistat

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

lansoprazole atazanavir

Applies to: amoxicillin / clarithromycin / lansoprazole and atazanavir / cobicistat

Using atazanavir together with lansoprazole is not recommended. By reducing stomach acid, lansoprazole can decrease the absorption and blood levels of atazanavir and make the medication less effective against HIV. Your doctor or pharmacist may be able to offer suggestions on safer alternatives if you require treatment for stomach acid or ulcer while you are being treated with atazanavir. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

clarithromycin lansoprazole

Applies to: amoxicillin / clarithromycin / lansoprazole and amoxicillin / clarithromycin / lansoprazole

Clarithromycin may increase the blood levels and side effects of lansoprazole in some people. Contact your doctor if you experience diarrhea or other intestinal problems. You may need a dose adjustment if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

clarithromycin atazanavir

Applies to: amoxicillin / clarithromycin / lansoprazole and atazanavir / cobicistat

Using clarithromycin together with atazanavir may alter the effects of clarithromycin. Contact your doctor if your condition worsens or if you have symptoms of irregular heartbeat, chest tightness, blurred vision or nausea. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

clarithromycin cobicistat

Applies to: amoxicillin / clarithromycin / lansoprazole and atazanavir / cobicistat

Using cobicistat together with clarithromycin may increase the blood levels and effects of both medications. Increased blood levels of clarithromycin can cause an irregular heart rhythm that may be serious. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

amoxicillin clarithromycin

Applies to: amoxicillin / clarithromycin / lansoprazole and amoxicillin / clarithromycin / lansoprazole

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

atazanavir food

Applies to: atazanavir / cobicistat

Food can enhance the levels of atazanavir in your body. To ensure maximal oral absorption, atazanavir should be administered with or immediately after a meal. This will make it easier for your body to absorb the medication.

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Minor

clarithromycin food

Applies to: amoxicillin / clarithromycin / lansoprazole

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer