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Drug interactions between amlodipine / hydrochlorothiazide / olmesartan and sarilumab

Results for the following 2 drugs:
amlodipine/hydrochlorothiazide/olmesartan
sarilumab

Interactions between your drugs

Moderate

amLODIPine sarilumab

Applies to: amlodipine / hydrochlorothiazide / olmesartan and sarilumab

Sarilumab may decrease the blood levels and effects of amLODIPine. You may need a dose adjustment if you have been receiving amLODIPine and are starting treatment with sarilumab. Likewise, if you have been receiving both medications, the dose of amLODIPine may need to be adjusted when sarilumab is discontinued. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

olmesartan food

Applies to: amlodipine / hydrochlorothiazide / olmesartan

If you are taking olmesartan you should avoid potassium-containing salt substitutes or over-the-counter potassium supplements without first talking to your doctor. This can cause high levels of potassium in your blood. High levels of potassium can cause weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs. Call your doctor at once if you have any of these symptoms.

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Minor

amLODIPine food

Applies to: amlodipine / hydrochlorothiazide / olmesartan

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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