Drug interactions between Amitiza and Zydelig
Interactions between your drugs
Applies to: Amitiza (lubiprostone) and Zydelig (idelalisib)
Idelalisib may cause serious and life-threatening diarrhea, and using it with other medications that also commonly cause diarrhea such as lubiprostone may increase that risk. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. Call your doctor immediately if the number of bowel movements per day increases by six or more, or if you experience new or worsening abdominal pain, chills, fever, nausea, or vomiting. You may need a dose adjustment or an interruption in idelalisib therapy if you develop severe diarrhea. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
No results found in our database - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.