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Drug Interactions between Ameluz and LymePak

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

doxycycline aminolevulinic acid topical

Applies to: LymePak (doxycycline) and Ameluz (aminolevulinic acid topical)

Aminolevulinic acid topical causes your skin to be more sensitive to light in areas where it has been applied. The risk and/or severity of reactions such as redness, scaling, swelling, stinging, and burning may be increased when it is used with other drugs that can also increase sensitivity to light such as doxycycline. You should avoid exposure to sunlight or bright indoor lights (examination lamps, operating room lamps, tanning beds, lights at close proximity) during and for 48 hours after treatment as directed by your doctor. Since sunscreens will not protect you against photosensitivity reactions associated with aminolevulinic acid topical, you should protect treated areas by wearing a wide-brimmed hat or other protective apparel if exposure to sunlight or other intense lights cannot be avoided. Be advised to reduce your light exposure if you experience sensations of stinging and/or burning. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

doxycycline food

Applies to: LymePak (doxycycline)

Iron can bind to doxycycline in the gastrointestinal tract, which may prevent their absorption into the bloodstream and possibly reduce their effectiveness. To avoid or minimize the interaction, iron-containing medications and doxycycline should preferably be taken at least three to four hours apart in most cases. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

doxycycline food

Applies to: LymePak (doxycycline)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.