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Drug interactions between Alka-Seltzer Gold and Comtrex Allergy Sinus Maximum Strength

Results for the following 2 drugs:
Alka-Seltzer Gold (citric acid/potassium bicarbonate/sodium bicarbonate)
Comtrex Allergy Sinus Maximum Strength (acetaminophen/chlorpheniramine/pseudoephedrine)

Interactions between your drugs


sodium bicarbonate pseudoephedrine

Applies to: Alka-Seltzer Gold (citric acid / potassium bicarbonate / sodium bicarbonate) and Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine)

Using pseudoephedrine together with sodium bicarbonate may increase the effects of pseudoephedrine. Contact your doctor if you experience tremor, anxiety, insomnia, irritability, or nervousness. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions


chlorpheniramine food

Applies to: Comtrex Allergy Sinus Maximum Strength (acetaminophen / chlorpheniramine / pseudoephedrine)

Alcohol can increase the nervous system side effects of chlorpheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with chlorpheniramine. Do not use more than the recommended dose of chlorpheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.