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Drug Interactions between aliskiren / amlodipine / hydrochlorothiazide and Hypaque Cysto

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

hydroCHLOROthiazide diatrizoate

Applies to: aliskiren / amlodipine / hydrochlorothiazide and Hypaque Cysto (diatrizoate)

Before you undergo any imaging procedure where diatrizoate may be given by injection, let your doctor know if you are currently being treated with hydroCHLOROthiazide. Injection of diatrizoate can sometimes cause kidney problems, and the risk may be increased if you are also using hydroCHLOROthiazide. The interaction may be more likely if you have preexisting kidney disease, congestive heart failure, or diabetes; or if you are elderly, dehydrated, or taking other medications that can affect the kidney. Depending on your health situation, your doctor may want you to stop using hydroCHLOROthiazide for a certain length of time before and after the procedure. You may also be asked to increase your fluid intake the day before the procedure, or you may be given intravenous fluids before, during, and after the procedure. Since diatrizoate contains iodine, also let your doctor know if you have had a previous reaction to iodine or iodine-containing products. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

amLODIPine diatrizoate

Applies to: aliskiren / amlodipine / hydrochlorothiazide and Hypaque Cysto (diatrizoate)

Before you undergo any imaging procedure where diatrizoate may be given by injection, let your doctor know if you are currently being treated with amLODIPine. Injection of diatrizoate can sometimes cause low blood pressure, and the risk may be increased if you are also using amLODIPine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

hydroCHLOROthiazide amLODIPine

Applies to: aliskiren / amlodipine / hydrochlorothiazide and aliskiren / amlodipine / hydrochlorothiazide

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

aliskiren food

Applies to: aliskiren / amlodipine / hydrochlorothiazide

Food can affect the absorption of aliskiren from the intestine. Therefore, you should take aliskiren at the same time each day exactly as prescribed by your doctor. You may take aliskiren with or without food, but take it the same way every time. This will help keep blood levels and effects of the medication steady. You should avoid drinking orange, apple, or grapefruit juice as much as possible during treatment with aliskiren. Studies have shown that drinking these juices regularly or within a short period before or after a dose of aliskiren can interfere with the absorption of the medication.

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Moderate

hydroCHLOROthiazide food

Applies to: aliskiren / amlodipine / hydrochlorothiazide

HydroCHLOROthiazide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

amLODIPine food

Applies to: aliskiren / amlodipine / hydrochlorothiazide

AmLODIPine and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

amLODIPine food

Applies to: aliskiren / amlodipine / hydrochlorothiazide

Using amLODIPine together with multivitamin with minerals can decrease the effects of amLODIPine. Talk with your doctor before using amLODIPine and multivitamin with minerals together. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

amLODIPine food

Applies to: aliskiren / amlodipine / hydrochlorothiazide

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.