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Drug Interactions between Actron and Minizide

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

ketoprofen prazosin

Applies to: Actron (ketoprofen) and Minizide (polythiazide / prazosin)

Using ketoprofen together with prazosin may decrease the effects of prazosin. Contact your doctor if your condition changes or if your blood pressure increases. If your doctor does prescribe these medications together, you may need a dose adjustment or need to check your blood pressure more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

ketoprofen polythiazide

Applies to: Actron (ketoprofen) and Minizide (polythiazide / prazosin)

Before taking polythiazide, tell your doctor if you also use ketoprofen. You may need dose adjustments or special tests in order to safely take both medications together. If you are receiving this combination drink plenty of water. Blood pressure and kidney function should be monitored as well. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.

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Moderate

prazosin polythiazide

Applies to: Minizide (polythiazide / prazosin) and Minizide (polythiazide / prazosin)

Before taking polythiazide, tell your doctor if you also use prazosin. You may need dose adjustments or special tests in order to safely take both medications together. The blood pressure lowering effects of this combination may be additive. You should take prazosin at bedtime and to notify your doctor if have dizziness or feel faint. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

ketoprofen food

Applies to: Actron (ketoprofen)

Ask your doctor before using ketoprofen together with ethanol. Do not drink alcohol while taking ketoprofen. Alcohol can increase your risk of stomach bleeding caused by ketoprofen. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

prazosin food

Applies to: Minizide (polythiazide / prazosin)

Ask your doctor before using prazosin together with ethanol. Using prazosin with ethanol can lower your blood pressure. This can cause dizziness or feeling like you might pass out, especially when getting up from a sitting or lying position. This may be more likely to occur when you first start taking either of these medications. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. You may develop flushing, warmth or redness under your skin or tingly feeling after alcohol intake (especially in you are of Asian descent) and should be advised to avoid alcohol or limit your intake. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

polythiazide food

Applies to: Minizide (polythiazide / prazosin)

Polythiazide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.