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Vicodin (acetaminophen / hydrocodone) Drug Interactions

Currently displaying 396 drugs known to have a major interaction with Vicodin (acetaminophen / hydrocodone).

See also: The most common drugs checked in combination with this medicine.

Check for interactions with Vicodin (acetaminophen / hydrocodone)

Type in a drug name and select a drug from the list.

Medications known to interact with Vicodin (acetaminophen / hydrocodone)

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  • olanzapine (Zyprexa, Zyprexa Zydis, Zyprexa Relprevv, Zyprexa Intramuscular)
  • ombitasvir / paritaprevir / ritonavir (Technivie)
  • orphenadrine (Norflex, Norflex Injectable, Banflex, Orphenate, Flexoject, Flexon, Myolin, Mio-Rel, Orfro, Antiflex)
  • oxazepam (Serax)
  • oxcarbazepine (Trileptal, Oxtellar XR)
  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Percolone, Oxyfast, RoxyBond, Dazidox, Oxecta, Roxicodone Intensol, Oxydose, M-Oxy, ETH-Oxydose, Endocodone)
  • oxymorphone (Opana, Opana ER, Numorphan, Numorphan HCl)
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  • verapamil (Calan, Verelan, Isoptin, Calan SR, Isoptin SR, Verelan PM, Covera-HS, Isoptin IV)
  • voriconazole (Vfend)
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Vicodin (acetaminophen / hydrocodone) alcohol/food Interactions

There is 1 alcohol/food interaction with Vicodin (acetaminophen / hydrocodone)

Vicodin (acetaminophen / hydrocodone) disease Interactions

There are 19 disease interactions with Vicodin (acetaminophen / hydrocodone) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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