Simplet (acetaminophen / chlorpheniramine / pseudoephedrine) Drug Interactions
A total of 987 drugs are known to interact with Simplet (acetaminophen / chlorpheniramine / pseudoephedrine).
- 213 major drug interactions
- 728 moderate drug interactions
- 46 minor drug interactions
Check for interactions with Simplet (acetaminophen / chlorpheniramine / pseudoephedrine)
Common medications checked in combination with Simplet (acetaminophen / chlorpheniramine / pseudoephedrine)
- amantadine (Symmetrel, Gocovri, Osmolex ER)
- Aspir 81 (aspirin)
- Calcium Concentrate (calcium carbonate)
- carbidopa / levodopa (Sinemet, Rytary, Sinemet CR, Duopa, Parcopa, Atamet)
- chondroitin / glucosamine (Osteo Bi-Flex, Cosamin DS, Schiff Move Free, Osteo Bi-Flex Triple Strength, Osteo Bi-Flex Double Strength, Cidaflex, Glucoten, OptiFlex Complete, Schiff Move Free Caplets, Relamine, Pryflex)
- cyclobenzaprine (Flexeril, Amrix, Fexmid, Comfort Pac with Cyclobenzaprine)
- daclatasvir (Daklinza)
- Evista (raloxifene)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- ibuprofen (Advil, Motrin, IBU, Proprinal, Advil Liqui-Gels, Motrin IB, IBU-200, Nuprin, Advil Infant's Concentrated Drops, Children's Motrin, Advil Children's, Ibu-8, Ibuprofen PMR, Caldolor, Motrin Childrens, Motrin Migraine Pain, Addaprin, Ibu-4, Ibu-Tab, Rufen, Midol IB, A-G Profen, Childrens Ibuprofen Berry, Advil Migraine, Ibu-6, Motrin Infant Drops, NeoProfen, Genpril, Haltran, Menadol, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
- Klor-Con M20 (potassium chloride)
- ledipasvir / sofosbuvir (Harvoni)
- Levoxyl (levothyroxine)
- Lyrica (pregabalin)
- omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
- Paracetamol (acetaminophen)
- Sinemet (carbidopa / levodopa)
- Singulair (montelukast)
- sofosbuvir (Sovaldi)
- Theragran-M (multivitamin with minerals)
- vitamin e (Centrum Singles-Vitamin E, Aqua Gem-E, E-600, E-Gems, Aquasol E, E Pherol, Amino-Opti-E, Vita-Plus E Natural, Alpha E, Nutr-E-Sol, E-400 Clear, Aquavite-E, Aqua-E, E-Max-1000)
- Wellbutrin (bupropion)
Simplet (acetaminophen / chlorpheniramine / pseudoephedrine) alcohol/food Interactions
There is 1 alcohol/food interaction with Simplet (acetaminophen / chlorpheniramine / pseudoephedrine)
Simplet (acetaminophen / chlorpheniramine / pseudoephedrine) disease Interactions
There are 13 disease interactions with Simplet (acetaminophen / chlorpheniramine / pseudoephedrine) which include:
- Alcoholism
- Liver Disease
- Anticholinergic Effects
- Asthma/Copd
- Cardiovascular Disease
- Pku
- Cardiovascular
- Renal/Liver Disease
- Gi Narrowing
- Pku
- Bph
- Diabetes
- Glaucoma
More about Simplet (acetaminophen / chlorpheniramine / pseudoephedrine)
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
