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Fioricet (acetaminophen / butalbital / caffeine) Drug Interactions

Currently displaying 215 drugs known to have a major interaction with Fioricet (acetaminophen / butalbital / caffeine).

See also: The most common drugs checked in combination with this medicine.

Check for interactions with Fioricet (acetaminophen / butalbital / caffeine)

Type in a drug name and select a drug from the list.

Medications known to interact with Fioricet (acetaminophen / butalbital / caffeine)

A B C D E F G H I L M N O P R S T W

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  • epinephrine / prilocaine (Citanest Forte)
  • ethanol (Alcohol (contained in alcoholic beverages), Ethyl Alcohol, Dehydrated Alcohol, Ablysinol, Alcohol 5% in Dextrose 5%, Alcohol And Dextrose Injections USP Hypertonic, Palcohol)
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  • guaifenesin / hydrocodone (Narcof, Vortex, Flowtuss, Hydrocod-GF, Maxi-Tuss HCG, Vicodin Tuss, Fentuss Expectorant, Vitussin Expectorant, Condasin, Obredon, CodiCLEAR DH, EndaCof-Tab, Ztuss ZT, Tusso-HC, Execlear, Hycotuss Expectorant, Pneumotussin HC, Propatuss Expectorant, Kwelcof, Vi-Q-Tuss, Co-Tussin, Codotuss, Co-Tuss V Expectorant, Vicoclear, Endacof XP, Hycosin Expectorant, Vicotuss, G-Tuss, Hycoclar Tuss, Cotuss V, Hydrotuss, Gua HC, Hycoclear, Medcodin, Pneumotussin 2.5, Entuss, Pneumotussin, Tusso-DF, Execof, Pancof XP, Touro HC, Xpect-HC, Atuss HX, Extendryl HC, Hydro-Tussin HG, Canges-XP, Z-Cof HCX, Monte-G HC, Tussicle, A-Cof DH, Relasin-HCX)
  • guaifenesin / hydrocodone / pheniramine / phenylephrine / phenylpropanolamine (S-T Forte)
  • guaifenesin / hydrocodone / pheniramine / phenylpropanolamine / pyrilamine
  • guaifenesin / hydrocodone / phenylephrine (Mintuss G, Atuss G, Ambi 5/15/100, Tussafed-HC, Levall 5.0, Hydro GP, De-Chlor G, Dynatuss HC, Tussafed-HCG, Uni-Lev 5.0, Crantex HC, Duratuss HD, Simuc-HD, Gentex HC, Donatussin DC, Guiaplex HC, Exetuss-HC, Qual-Tussin DC, Nariz HC, MonteFlu HC, Nazarin HC, HydroFed)
  • guaifenesin / hydrocodone / pseudoephedrine (Hycofenix, Entuss-D JR, Decotuss-HD, Vanex Expectorant, Tussadur-HD, Tussend Expectorant, Detussin Expectorant, Tussgen Expectorant, SRC Expectorant, Nalex Expectorant, Deconamine CX, Poly-Tussin XP, Entuss-D, Hydrotussin HD, KG-Tuss HD, Medtuss HD, Spantuss HD, Vanacon, Su-Tuss HD Elixir, Tussafin Liquid, Hytussin Expectorant, Drituss HD, Hydro-Tuss XP, Dynex HD, Entex HC, Pseudatex HC)
  • guaifenesin / hydromorphone (Dilaudid Cough Syrup)
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  • leflunomide (Arava)
  • levomethadyl acetate (Orlaam)
  • levorphanol (Levo-Dromoran)
  • lidocaine / prilocaine topical (Emla, Oraqix, Lidopril, Anodyne LPT, DermacinRx Prizopak, Prilovix, Livixil Pak, Dolotranz, Lidopril XR, Prikaan, Relador Pak Plus, AgonEaze, Venipuncture CPI, Prilovix Plus, Emla Anesthetic Disc, Medolor Pak, Prilolid, LiproZonePak, DermacinRx Empricaine, DermacinRx Prikaan, Leva Set)
  • lomitapide (Juxtapid)
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  • meperidine (Demerol, Meperitab)
  • meperidine / promethazine (Mepergan, Meprozine, Mepergan Fortis)
  • methadone (Methadose, Dolophine, Methadone Diskets, Methadose Sugar-Free)
  • mipomersen (Kynamro)
  • morphine (MS Contin, Morphine Sulfate ER, Morphine Sulfate IR, Roxanol, Kadian, MSIR, MorphaBond ER, Duramorph, Statex, Avinza, Morphine Sulfate SR, Arymo ER, Morphine LP Epidural, Astramorph PF, Oramorph SR, Mitigo, Morphine Rapi-Ject, M-Eslon, RMS, Infumorph, Duramorph PF, OMS, Roxanol 100, Rescudose, MS/S, Roxanol-T, Doloral, Doloral Sirop, Morphitec, M O S)
  • morphine liposomal (DepoDur)
  • morphine / naltrexone (Embeda)
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  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Percolone, RoxyBond, Oxydose, Oxyfast, Oxecta, Dazidox, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol)
  • oxymorphone (Opana, Opana ER, Numorphan HCl, Numorphan)
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  • tapentadol (Nucynta, Nucynta ER)
  • teriflunomide (Aubagio)
  • tizanidine (Zanaflex)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, ConZip, Larapam SR, Ryzolt, Tramal SR, GenRx Tramadol, Zamadol, Tramedo, Zydol, Tramahexal SR, Tramahexal, Zydol XL, Rybix ODT, Ultram ODT)
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Fioricet (acetaminophen / butalbital / caffeine) alcohol/food interactions

There are 6 alcohol/food interactions with Fioricet (acetaminophen / butalbital / caffeine)

Fioricet (acetaminophen / butalbital / caffeine) disease interactions

There are 23 disease interactions with Fioricet (acetaminophen / butalbital / caffeine) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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