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Fioricet (acetaminophen / butalbital / caffeine) Drug Interactions

Currently displaying 215 drugs known to have a major interaction with Fioricet (acetaminophen / butalbital / caffeine).

See also: The most common drugs checked in combination with this medicine.

Check for interactions with Fioricet (acetaminophen / butalbital / caffeine)

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Medications known to interact with Fioricet (acetaminophen / butalbital / caffeine)

A B C D E F G H I L M N O P R S T W

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  • epinephrine / prilocaine (Citanest Forte)
  • ethanol (Alcohol (contained in alcoholic beverages), Ethyl Alcohol, Alcohol 5% in Dextrose 5%, Alcohol And Dextrose Injections USP Hypertonic, Palcohol, Dehydrated Alcohol, Ablysinol)
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  • guaifenesin / hydrocodone (Execlear, Narcof, Hydrocod-GF, Vortex, Condasin, Flowtuss, Kwelcof, Fentuss Expectorant, Vicotuss, Pneumotussin 2.5, Monte-G HC, Obredon, CodiCLEAR DH, Maxi-Tuss HCG, EndaCof-Tab, Ztuss ZT, Tusso-HC, Vicodin Tuss, Hycotuss Expectorant, Pneumotussin HC, Propatuss Expectorant, Vi-Q-Tuss, Co-Tussin, Codotuss, Co-Tuss V Expectorant, Vicoclear, Endacof XP, Hycosin Expectorant, G-Tuss, Hycoclar Tuss, Cotuss V, Vitussin Expectorant, Hydrotuss, Gua HC, Hycoclear, Medcodin, Entuss, Pneumotussin, Tusso-DF, Execof, Pancof XP, Touro HC, Xpect-HC, Atuss HX, Extendryl HC, Hydro-Tussin HG, Canges-XP, Z-Cof HCX, Tussicle, A-Cof DH, Relasin-HCX)
  • guaifenesin / hydrocodone / pheniramine / phenylephrine / phenylpropanolamine (S-T Forte)
  • guaifenesin / hydrocodone / pheniramine / phenylpropanolamine / pyrilamine
  • guaifenesin / hydrocodone / phenylephrine (Mintuss G, Atuss G, Ambi 5/15/100, Tussafed-HC, Levall 5.0, Hydro GP, De-Chlor G, Dynatuss HC, Tussafed-HCG, Uni-Lev 5.0, Crantex HC, Duratuss HD, Simuc-HD, Gentex HC, Donatussin DC, Guiaplex HC, Exetuss-HC, Qual-Tussin DC, Nariz HC, MonteFlu HC, Nazarin HC, HydroFed)
  • guaifenesin / hydrocodone / pseudoephedrine (Hycofenix, Entuss-D JR, Decotuss-HD, Vanex Expectorant, Tussadur-HD, Tussend Expectorant, Detussin Expectorant, Tussgen Expectorant, SRC Expectorant, Nalex Expectorant, Deconamine CX, Poly-Tussin XP, Entuss-D, Hydrotussin HD, KG-Tuss HD, Medtuss HD, Spantuss HD, Vanacon, Su-Tuss HD Elixir, Tussafin Liquid, Hytussin Expectorant, Drituss HD, Hydro-Tuss XP, Dynex HD, Entex HC, Pseudatex HC)
  • guaifenesin / hydromorphone (Dilaudid Cough Syrup)
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  • meperidine (Demerol, Meperitab)
  • meperidine / promethazine (Mepergan, Meprozine, Mepergan Fortis)
  • methadone (Methadose, Dolophine, Methadone Diskets, Methadose Sugar-Free)
  • mipomersen (Kynamro)
  • morphine (MS Contin, Morphine Sulfate ER, Roxanol, Morphine Sulfate IR, Kadian, MSIR, MorphaBond ER, Morphine Sulfate SR, Duramorph, Avinza, Morphine LP Epidural, Oramorph SR, Arymo ER, Statex, Astramorph PF, Mitigo, Morphine Rapi-Ject, Roxanol-T, RMS, Infumorph, Duramorph PF, OMS, Roxanol 100, Rescudose, MS/S, Doloral, Doloral Sirop, M-Eslon, Morphitec, M O S)
  • morphine liposomal (DepoDur)
  • morphine / naltrexone (Embeda)
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  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Percolone, Oxyfast, Dazidox, RoxyBond, Oxecta, Oxydose, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol)
  • oxymorphone (Opana, Opana ER, Numorphan, Numorphan HCl)
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  • tapentadol (Nucynta, Nucynta ER)
  • teriflunomide (Aubagio)
  • tizanidine (Zanaflex)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Tramedo, Ultram ER, Larapam SR, GenRx Tramadol, ConZip, Zydol, Ryzolt, Tramahexal, Zamadol, Tramal SR, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
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Fioricet (acetaminophen / butalbital / caffeine) alcohol/food interactions

There are 6 alcohol/food interactions with Fioricet (acetaminophen / butalbital / caffeine)

Fioricet (acetaminophen / butalbital / caffeine) disease interactions

There are 23 disease interactions with Fioricet (acetaminophen / butalbital / caffeine) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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