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Bupap (acetaminophen / butalbital) Drug Interactions

A total of 993 drugs are known to interact with Bupap (acetaminophen / butalbital).

  • 199 major drug interactions
  • 704 moderate drug interactions
  • 90 minor drug interactions

Show all medications in the database that may interact with Bupap (acetaminophen / butalbital).

Check for interactions

Type in a drug name to check for interactions with Bupap (acetaminophen / butalbital).

Most frequently checked interactions

View interaction reports for Bupap (acetaminophen / butalbital) and the medicines listed below.

  • Adderall (amphetamine / dextroamphetamine)
  • Advil (ibuprofen)
  • Ambien (zolpidem)
  • amitriptyline (Elavil, Endep, Vanatrip)
  • Benadryl (diphenhydramine)
  • caffeine (Vivarin, Stay Awake, NoDoz, Jet Alert Regular Strength, Jet Alert Maximum Strength, Caffedrine, Alert, Diurex Ultra, Cafcit, Jet Alert Double Strength, ConRx Alert, Pep-Back ReCharge, Pep-Back Peak Performance, Keep Alert, Verv, Stat Awake, Stay Alert, NoDoz Maximum Strength, Wakespan, Lucidex, Diurex Maximum Relief Water Caps, Pep-Back Ultra, 357 HR Magnum, Enerjets, Fastlene, Keep Going, Molie, Overtime, Valentine)
  • clonazepam (Klonopin, Klonopin Wafer)
  • codeine
  • Cymbalta (duloxetine)
  • Flexeril (cyclobenzaprine)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • hydrochlorothiazide (HydroDIURIL, Microzide, Oretic, Esidrix, Ezide, Aquazide H, Hydro Par, Carozide, Diaqua, Loqua)
  • hydrocodone (Hysingla ER, Zohydro ER, Vantrela ER)
  • ibuprofen (Advil, Motrin, IBU, Children's Motrin, Proprinal, Advil Liqui-Gels, Ibu-8, Motrin IB, Motrin Childrens, Rufen, Childrens Ibuprofen Berry, IBU-200, Ibuprofen PMR, Advil Migraine, Ibu-Tab, Genpril, Menadol, Advil Children's, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Addaprin, Motrin Infant Drops, NeoProfen, Caldolor, Motrin Pediatric, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • Klonopin (clonazepam)
  • Lortab (acetaminophen / hydrocodone)
  • Lyrica (pregabalin)
  • Nexium (esomeprazole)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Phenergan (promethazine)
  • promethazine (Phenergan, Promethegan, Phenadoz, Phenoject-50, Anergan 50, Adgan, Phenazine 50, Phenergan Fortis, Antinaus 50, V-Gan-50, V-Gan-25, Pro-Med)
  • tizanidine (Zanaflex)
  • Topamax (topiramate)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, ConZip, Zydol, Tramal SR, GenRx Tramadol, Zamadol, Ryzolt, Tramedo, Larapam SR, Tramahexal SR, Tramahexal, Zydol XL, Rybix ODT, Ultram ODT)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)

Bupap (acetaminophen / butalbital) alcohol/food interactions

There is 1 alcohol/food interaction with Bupap (acetaminophen / butalbital)

Bupap (acetaminophen / butalbital) disease interactions

There are 14 disease interactions with Bupap (acetaminophen / butalbital) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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