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Bupap (acetaminophen / butalbital) Drug Interactions

A total of 990 drugs are known to interact with Bupap (acetaminophen / butalbital).

  • 199 major drug interactions
  • 701 moderate drug interactions
  • 90 minor drug interactions

Show all medications in the database that may interact with Bupap (acetaminophen / butalbital).

Check for interactions with Bupap (acetaminophen / butalbital)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Bupap (acetaminophen / butalbital)

  • Adderall (amphetamine / dextroamphetamine)
  • Advil (ibuprofen)
  • Ambien (zolpidem)
  • amitriptyline (Elavil, Endep, Vanatrip)
  • Benadryl (diphenhydramine)
  • caffeine (Vivarin, Alert, NoDoz, Caffedrine, Cafcit, Keep Going, Jet Alert Regular Strength, Jet Alert Double Strength, Jet Alert Maximum Strength, ConRx Alert, Pep-Back ReCharge, Pep-Back Peak Performance, Keep Alert, Stay Awake, Verv, Stat Awake, Stay Alert, NoDoz Maximum Strength, Wakespan, Lucidex, Diurex Maximum Relief Water Caps, Diurex Ultra, Pep-Back Ultra, 357 HR Magnum, Enerjets, Fastlene, Molie, Overtime, Valentine)
  • clonazepam (Klonopin, Klonopin Wafer)
  • codeine
  • Cymbalta (duloxetine)
  • Flexeril (cyclobenzaprine)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • hydrochlorothiazide (HydroDIURIL, Microzide, Esidrix, Oretic, Diaqua, Aquazide H, Hydro Par, Ezide, Carozide, Loqua)
  • hydrocodone (Hysingla ER, Zohydro ER, Vantrela ER)
  • ibuprofen (Advil, Motrin, IBU, Proprinal, Advil Liqui-Gels, Motrin IB, IBU-200, Nuprin, Children's Motrin, Motrin Migraine Pain, Advil Migraine, Caldolor, Ibuprofen PMR, Advil Children's, Addaprin, NeoProfen, Advil Infant's Concentrated Drops, A-G Profen, Motrin Childrens, Childrens Ibuprofen Berry, Ibu-6, Ibu-8, Motrin Infant Drops, Ibu-Tab, Rufen, Genpril, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • Klonopin (clonazepam)
  • Lortab (acetaminophen / hydrocodone)
  • Lyrica (pregabalin)
  • Nexium (esomeprazole)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Phenergan (promethazine)
  • promethazine (Phenergan, Promethegan, Phenadoz, Antinaus 50, Anergan 50, Adgan, Phenazine 50, Phenergan Fortis, V-Gan-50, V-Gan-25, Phenoject-50, Pro-Med)
  • tizanidine (Zanaflex)
  • Topamax (topiramate)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Tramedo, Ultram ER, Larapam SR, GenRx Tramadol, ConZip, Zydol, Ryzolt, Tramahexal, Zamadol, Tramal SR, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)

Bupap (acetaminophen / butalbital) alcohol/food interactions

There is 1 alcohol/food interaction with Bupap (acetaminophen / butalbital)

Bupap (acetaminophen / butalbital) disease interactions

There are 14 disease interactions with Bupap (acetaminophen / butalbital) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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