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Drug Interactions between ACAM2000 and bromfenac / gatifloxacin / prednisolone ophthalmic

This report displays the potential drug interactions for the following 2 drugs:

  • ACAM2000 (smallpox vaccine)
  • bromfenac/gatifloxacin/prednisolone ophthalmic

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Interactions between your drugs


prednisoLONE ophthalmic smallpox vaccine

Applies to: bromfenac / gatifloxacin / prednisolone ophthalmic and ACAM2000 (smallpox vaccine)

If you are currently being treated or have recently been treated with a steroid such as prednisoLONE ophthalmic, you should talk to your doctor before receiving smallpox vaccine. Depending on the dose and length of time you have been on the steroid, you may be at risk for developing an infection or other side effects from the vaccine, or have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of prednisoLONE ophthalmic therapy. If you have recently been vaccinated with smallpox vaccine, your doctor may choose to postpone treatment with prednisoLONE ophthalmic for a couple of weeks. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions


bromfenac food

Applies to: bromfenac / gatifloxacin / prednisolone ophthalmic

Food significantly decreases the levels of bromfenac. Avoid eating a high-fat meal. Take bromfenac on an empty stomach at least 30 minutes before or 2 hours after a meal. This will make it easier for your body to absorb the medication.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.