Skip to Content

Tricyclic antidepressants

What are Tricyclic antidepressants

Tricyclic antidepressants (often abbreviated to TCAs) are a class of drugs that are traditionally used to treat depression; however, they may also be used in the treatment of other mood disorders, to relieve chronic nerve-related pain, to reduce bed-wetting, to manage obsessive compulsive behaviors, and to prevent migraines.

TCAs increase levels of norepinephrine and serotonin by inhibiting their reuptake, and also block the actions of another neurotransmitter, acetylcholine. Some TCAs also affect histamine. Affinities for these neurotransmitters differ among various TCAs, which explains why some TCAs are more effective than others for certain conditions or are more likely than others to cause side effects such as constipation, dry mouth, and sedation.

List of Tricyclic antidepressants:

Filter by:
Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
amoxapine systemic (Pro, More...)
5 reviews
   
9.5
desipramine systemic (Pro, More...)
19 reviews
   
8.7
clomipramine systemic (Pro, More...)
100 reviews
   
8.3
trimipramine systemic (Pro, More...)
1 review
   
8.0
amitriptyline systemic (Pro, More...)
876 reviews
   
7.7
nortriptyline systemic (Pro, More...)
313 reviews
   
7.6
imipramine systemic (Pro, More...)
30 reviews
   
7.3
protriptyline systemic (Pro, More...)
1 review
   
7.0
doxepin systemic (Pro, More...)
216 reviews
   
6.9
Hide