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Factor Xa inhibitors

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Factor Xa inhibitors are anticoagulants that block the activity of clotting factor Xa and prevents blood clots developing or getting worse. Factor Xa is generated by both the extrinsic and intrinsic coagulation pathways, it activates prothrombin to thrombin, which activates the final components of the coagulation pathway to form clots.

Factor Xa inhibitors are generally used as prophylaxis in patients having hip and knee replacement surgery, where blood clots can form and lead to deep vein thrombosis and pulmonary embolism.

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