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Bisphosphonates

What are Bisphosphonates

Bisphosphonates are drugs that inhibit mineralization or resorption of the bone by blocking the action of osteoclasts. Bisphosphonates are enzyme-resistant analogues of pyrophosphate, which normally inhibits mineralization in the bone. Their effect is dose dependent and they reduce the turnover of bone by inhibiting recruitment and promoting apoptosis of osteoclasts. Bisphosphonates are used to treat postmenopausal and glucocorticoid induced osteoporosis, Paget's disease of bone and malignant hypercalcemia. There are a few bisphosphonates available and one might work better for a particular condition, than the other.

List of Bisphosphonates:

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Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
Fosamax Plus D (Pro, More...)
generic name: alendronate/cholecalciferol
0 reviews
   
9.5
Didronel (Pro, More...)
generic name: etidronate
0 reviews
   
7.0
Zometa (Pro, More...)
generic name: zoledronic acid
17 reviews
   
6.7
Reclast (Pro, More...)
generic name: zoledronic acid
36 reviews
   
6.3
Boniva (Pro, More...)
generic name: ibandronate
28 reviews
   
5.5
Aclasta (More...)
generic name: zoledronic acid
3 reviews
   
5.2
Atelvia (Pro, More...)
generic name: risedronate
3 reviews
   
4.7
Fosamax (Pro, More...)
generic name: alendronate
13 reviews
   
4.7
Actonel (Pro, More...)
generic name: risedronate
15 reviews
   
3.8
Actonel with Calcium (Pro, More...)
generic name: calcium carbonate/risedronate
1 review
   
3.0
Aredia (Pro, More...)
generic name: pamidronate
0 reviews
   
0.0
Binosto (Pro, More...)
generic name: alendronate
0 reviews
   
0.0
Skelid (Pro, More...)
generic name: tiludronate
0 reviews
   
0.0
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