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Son formula tablets

Description

SON Formula (MAP ) is a patented dietary proteins substitute, which provides a unique pattern of essential amino acids, in a highly purified, free, crystalline form. After oral ingestion, SON Formula is rapidly utilized. SON Formula does not require the aid of peptidases and therefore, it is absorbed, within 23 minutes, through the first 100 cm of functional small intestine. SON Formula does not provide any fecal residue. SON Formula is amphoteric. SON Formula is supplied in tablets of 1,000 mg for oral administration. Each tablet of SON Formula , in addition to the active ingredient MAP , contains no inactive ingredients.

COMPOSITION

SON Formula , in a dose of 10 g, provides the following essential amino acids profile:

L - Leucine                                1.964 g

L - Valine                                  1.657 g

L - Isoleucine                             1.483 g

L - Lysine                                  1.429 g

L - Phenylalanine                        1.289 g

L - Threonine                             1.111 g

L - Methionine                           0.699 g

L - Tryptophan                          0.368 g

Clinical Studies

The results of a comparative, double-blind, triple crossover Net Nitrogen Utilization (NNU) clinical study have shown that the subjects, while taking MAP , as a dietary proteins substitute, achieved a body's 99% NNU. This means that 99% of MAP's constituent amino acids followed the anabolic pathway, thus acting as precursor of body's protein synthesis. By comparison, dietary proteins only provide between 16 to 48% NNU. This fact evidences that MAP is more nutritious than dietary proteins. This has been confirmed by the fact that during the study, each subject body's nitrogen balance was maintained in equilibrium by taking MAP, as a sole and total substitute of dietary proteins, in a dosage of only 400 mg/kg/day, which provided less than 2 kcal/day (1g MAP= 0.04 Kcal). The study results have also shown that 1% of MAP's constituent amino acids followed the catabolic pathway, thus releasing only 1% of nitrogen catabolites and energy. By comparison dietary proteins release between 52% to 84% nitrogen catabolites and energy. This fact evidences that MAP is safer than dietary proteins, and that provides the lowest amount of energy in comparison to any dietary protein.

To illustrate:  when a dietary protein is digested, it releases its constituent amino acids into the small intestine, where they are absorbed. Then, those amino acids can follow either the anabolic pathway or the catabolic pathway (Fig. I).

images/73/91070001.jpg

When dietary amino acids follow the anabolic pathway , they act as precursors for the body's protein synthesis, thus becoming the body's constituent proteins. Throughout the anabolic pathway , amino acids do not release any nitrogen catabolites or energy (Fig. II).

images/73/91070002.jpg

On the other hand, when dietary amino acids follow the catabolic pathway , they act only as a source of energy and not as precursors of body's proteins synthesis. Throughout the catabolic pathway , amino acids do release nitrogen catabolites and energy (Fig. III).

images/73/91070003.jpg

Indications and Usage

SON Formula is indicated as a safe and effective substitute for dietary proteins.

SON Formula Vs Dietary Proteins
Characteristics SON Formula Dietary Proteins
Net Nitrogen Utilization (NNU)
99%
16%- 48%
Nitrogen Catabolites
1%
52%-84%
Body's Protein Synthesis
10g
Approx. 350g
Energy
0.04 Kcal/g
4 Kcal/g
Digestion
Approx. 23 minutes
3-5 hours
Contraindications
None
Renal Failure or Hepatic Failure
Adverse Reactions
None
Food Sensitivities
Shelf-Life
3 years
1-4 days
Refrigeration
Not needed
Needed
Volume
Approx. 30cc.
500-1000cc.

Adverse Reactions

No adverse reactions have been reported.

Overdosage

No adverse reactions have been reported.

Dosage and Administration

SON Formula should be administered with food. SON Formula in a dosage of 400mg/kg/day has been shown to be adequate, as a sole and total substitute of dietary proteins, to maintain the body's nitrogen balance in equilibrium. To calculate the SON Formula dosage necessary to substitute dietary proteins, apply the following:

SON Formula dosage = (Dietary Protein × 0.4) g



For instance:  to calculate the dosage of SON Formula necessary to substitute 10 g of dietary proteins, proceed as follows:

  1. SON Formula dosage = (Dietary Proteins × 0.4) g
  2. SON Formula dosage = (10 × 0.4) g
  3. SON Formula dosage = 4 g

Therefore, 4 g of SON Formula provide a body's protein synthesis equivalent to that provided by 10 g of high biological value dietary proteins.

SUPPLY INFORMATION

SON Formula , is available in bottles of 100 tablets of 1,000 mg, for oral administration.

Additional professional information on SON Formula is available thorough the International Nutritional Research Center, Inc.

Patent No. 5,132,113

COPYRIGHT © International Nutrition Research Center, Inc., 2003

All rights reserved

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