Spectracef Dosage

Medically reviewed by Drugs.com. Last updated on March 17, 2021.

Generic name: CEFDITOREN PIVOXIL 200mg
Dosage form: tablet, film coated

(See INDICATIONS AND USAGE for Indicated Pathogens.)

SPECTRACEF® (cefditoren pivoxil) Dosage and Administration* Adults and Adolescents (≥12 Years)
Type of Infection	Dosage	Duration (Days)
Community-Acquired Pneumonia	400 mg BID	14
Acute Bacterial Exacerbation of Chronic Bronchitis	400 mg BID	10
Pharyngitis/Tonsillitis	200mg BID
Uncomplicated Skin and Skin Structure Infections	200mg BID

*Should be taken with meals

Patients with Renal Insufficiency

No dose adjustment is necessary for patients with mild renal impairment (CLcr: 50-80 mL/min/1.73 m2). It is recommended that not more than 200 mg BID be administered to patients with moderate renal impairment (CLcr: 30-49 mL/min/1.73 m2) and 200 mg QD be administered to patients with severe renal impairment (CLcr: <30 mL/min/1.73 m2). The appropriate dose in patients with end-stage renal disease has not been determined.

Patients with Hepatic Disease

No dose adjustments are necessary for patients with mild or moderate hepatic impairment (Child-Pugh Class A or B). The pharmacokinetics of cefditoren have not been studied in patients with severe hepatic impairment (Child-Pugh Class C).