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Bretzri Dosage

Medically reviewed by Last updated on July 23, 2020.

Dosage form: aerosol, metered

Recommended Dosage and Administration

The recommended dosage of BREZTRI AEROSPHERE is budesonide 320 mcg, glycopyrrolate 18 mcg and formoterol fumarate 9.6 mcg (administered as 2 inhalations of BREZTRI AEROSPHERE [budesonide/glycopyrrolate/formoterol fumarate 160 mcg/9 mcg/4.8 mcg]) twice daily in the morning and in the evening by oral inhalation. Do not take more than two inhalations twice daily.

After inhalation, rinse mouth with water without swallowing.


Prime BREZTRI AEROSPHERE before using for the first time. Priming BREZTRI AEROSPHERE is essential to ensure appropriate drug content in each actuation. Prime BREZTRI AEROSPHERE by releasing 4 sprays into the air away from the face, shaking well before each spray.

If the inhaler has not been used for more than 7 days, is dropped, or after weekly cleaning, prime the inhaler again by releasing 2 sprays into the air away from the face, shaking well before each spray.

Dose counter

BREZTRI AEROSPHERE canister has an attached dose indicator, which indicates how many inhalations remain. The dose indicator display will move after every tenth actuation. When nearing the end of the usable inhalations, the color behind the number in the dose indicator display window changes to red. BREZTRI AEROSPHERE should be discarded when the dose indicator display window shows zero.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.