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Ammonul (sodium benzoate / sodium phenylacetate) Disease Interactions

There is 1 disease interaction with Ammonul (sodium benzoate / sodium phenylacetate):


Sodium salts (Includes Ammonul) ↔ sodium/water imbalance

Severe Potential Hazard, High plausibility. Applies to: Hypernatremia, Hypokalemia, Fluid Retention, Congestive Heart Failure

Sodium chloride can induce sodium and water retention and result in hypernatremia, hypokalemia, edema and aggravation of congestive heart failure. Therapy with sodium- containing agents should be administered with extreme caution, if at all, in patients with congestive heart failure, severe renal insufficiency, and in clinical states where there is edema with sodium retention. Clinical monitoring of acid/base balance and electrolytes prior to, during, a following completion of therapy with sodium- containing agents is recommended.


  1. "Product Information. Megace (megestrol)." Bristol-Myers Squibb, Princeton, NJ.
  2. "Product Information. Calcibind (cellulose sodium phosphate)." Mission Pharmaceutical Company, San Antonio, TX.
  3. "Product Information. Sodium Benzoate (sodium benzoate)." Taylor Pharmaceuticals, San Clemente, CA.

Ammonul (sodium benzoate / sodium phenylacetate) drug interactions

There are 5 drug interactions with Ammonul (sodium benzoate / sodium phenylacetate)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.