Skip to Content

Veltassa (patiromer) Disease Interactions

There are 2 disease interactions with Veltassa (patiromer):


Patiromer (Includes Veltassa) ↔ gastrointestinal motility

Severe Potential Hazard, Moderate plausibility. Applies to: Gastrointestinal Obstruction, Constipation

The use of patiromer should be avoided in patients with severe constipation, bowel obstruction or impaction, including abnormal post-operative bowel motility disorders, as this agent may be ineffective and may worsen gastrointestinal conditions. Therapy with patiromer should be administered cautiously in patients with a history of bowel obstruction or major gastrointestinal surgery, severe gastrointestinal disorders, or swallowing disorders.


Patiromer (Includes Veltassa) ↔ hypomagnesemia

Moderate Potential Hazard, Moderate plausibility. Applies to: Diarrhea, Magnesium Imbalance

Patiromer binds to magnesium in the colon, which can lead to hypomagnesemia. It is recommended to monitor serum magnesium concentrations during therapy. Therapy with patiromer should be administered cautiously in patients with or predisposed to magnesium deficiency. Consider magnesium supplementation in patients who develop low serum magnesium levels.

Veltassa (patiromer) alcohol/food interactions

There is 1 alcohol/food interaction with Veltassa (patiromer)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.