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Papacon (papaverine) Disease Interactions

There is 1 disease interaction with Papacon (papaverine):

Major

Papaverine derivatives (Includes Papacon) ↔ complete AV heart block

Severe Potential Hazard, High plausibility. Applies to: Heart Block

The use of papaverine and papaverine derivatives is contraindicated in patients with complete AV heart block. When conduction is depressed, these agents can induce transient ectopic rhythms of ventricular origin, either premature beats or paroxysmal tachycardia. Therapy with these agents should be administered cautiously in patients with conduction disturbances, including sinus bradyarrhythmia and partial or first-degree AV block.

References

  1. "Product Information. Papacon (papaverine)." Hoechst Marion-Roussel Inc, Kansas City, MO.

Papacon (papaverine) drug interactions

There are 260 drug interactions with Papacon (papaverine)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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