Namenda (memantine) Disease Interactions
There are 2 disease interactions with Namenda (memantine):
Memantine (Includes Namenda) ↔ hepatic impairment
Moderate Potential Hazard, Moderate plausibility. Applies to: Liver Disease
Memantine should be used with caution in patients with severe hepatic impairment and a dosage reduction is recommended. No dosage adjustment is needed in patients with mild or moderate hepatic impairment.
Memantine (Includes Namenda) ↔ renal impairment
Moderate Potential Hazard, Moderate plausibility. Applies to: Renal Dysfunction, Urinary Tract Infection
Memantine renal clearance involves active tubular secretion moderated by pH dependent tubular reabsorption and conditions that raise urine pH may increase the plasma levels of memantine. Therapy with memantine should be used cautiously in patients with conditions that raise urine pH, such as renal tubular acidosis or severe infections of the urinary tract. Additionally, memantine should be used with caution in patients with severe renal impairment and a dosage reduction is recommended. No dosage adjustment is needed in patients with mild or moderate renal impairment.
Namenda (memantine) drug interactions
There are 491 drug interactions with Namenda (memantine)
Namenda (memantine) alcohol/food interactions
There is 1 alcohol/food interaction with Namenda (memantine)
More about Namenda (memantine)
- Namenda Side Effects
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- 17 Reviews
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- Drug class: miscellaneous central nervous system agents
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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