Optiray 300 (ioversol) Disease Interactions
There are 5 disease interactions with Optiray 300 (ioversol):
Iodinated radiopaque contrast agents (Includes Optiray 300) ↔ hyperthyroidism
Severe Potential Hazard, Moderate plausibility. Applies to: Hyperthyroidism
Reports of thyroid storm following the use of iodinated diagnostic agents in patients with hyperthyroidism or with an autonomously functioning thyroid nodule suggest that this additional risk be evaluated in such patients before the use of any contrast medium. Some agents such as ioversol are contraindicated in symptomatic hyperthyroidism.
Radiopaque contrast agents (Includes Optiray 300) ↔ pheochromocytoma
Severe Potential Hazard, Moderate plausibility. Applies to: Pheochromocytoma
Administration of radiopaque materials to patients known or suspected of having pheochromocytoma should be performed with extreme caution. If, in the opinion of the physician, the possible benefits of such procedures outweigh the considered risk, the procedures should be performed with the absolute minimum amount of injected radiopaque medium. The blood pressure should be assessed throughout the procedure and measures for treatment of a hypertensive crisis should be available.
Contrast agents (Includes Optiray 300) ↔ sickle cell disease
Moderate Potential Hazard, Moderate plausibility. Applies to: Sickle Cell Anemia
Some contrast agents have shown to promote the phenomenon of sickling (blood cell rupture) in individuals who are homozygous for sickle cell disease when administered intravenously or intra- arterially. Caution is advised.
Ioversol (Includes Optiray 300) ↔ acute renal failure
Moderate Potential Hazard, Moderate plausibility. Applies to: Renal Dysfunction, Diabetes Mellitus, Multiple Myeloma, Congestive Heart Failure
Acute kidney injury, including renal failure, may occur after ioversol administration. Risk factors include preexisting renal impairment, dehydration, diabetes, congestive heart failure, advanced vascular disease, multiple myeloma, elderly age, and concomitant use of nephrotoxic or diuretic medications. The lowest dose of ioversol should be used in patients with renal impairment and other risk factors.
Ioversol (Includes Optiray 300) ↔ cardiovascular disease
Moderate Potential Hazard, Moderate plausibility. Applies to: Renal Dysfunction, Congestive Heart Failure, Cardiovascular Disease, Liver Disease
Life-threatening or fatal cardiovascular reactions have occurred with the use of ioversol, including cardiac arrest, hypotensive collapse and shock. Most deaths have occurred following 10 minutes of the injection, and cardiovascular disease has been identified as the main underlying factor. Additionally, ioversol increases the circulatory osmotic load and may induce acute or delayed hemodynamic disturbances in patients with congestive heart failure, and severely impaired renal function with or without hepatic disease. Caution should be used when using ioversol in these patients and the lowest dose possible should be used.
Optiray 300 (ioversol) drug interactions
There are 240 drug interactions with Optiray 300 (ioversol)
More about Optiray 300 (ioversol)
- Optiray 300 Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: non-ionic iodinated contrast media
- FDA Alerts (1)
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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