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DaTscan Disease Interactions

There are 2 disease interactions with DaTscan (ioflupane I 123).

Moderate

Ioflupane I-123 (applies to DaTscan) renal impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

Ioflupane I-123 is excreted by the kidney and patients with severe renal impairment may have increased radiation exposure and altered DaTscan images. Use with caution in these patients.

References

  1. "Product Information. DaTscan (ioflupane I-123)." GE Healthcare (2022):
Moderate

Ioflupane I-123 (applies to DaTscan) thyroid dysfunction

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Thyroid Disease

Ioflupane I-123 injection may contain up to 6% of free iodide (iodine 123). To decrease thyroid accumulation of iodine 123, it is recommended to block the thyroid gland before administration of this agent. Failure to block thyroid uptake of iodine 123 may result in an increased long term risk for thyroid neoplasia. Avoid the use of Potassium Iodide Oral Solution or Lugol's Solution in patients who are sensitive to such products. Care is recommended when using this agent in patients with thyroid disease.

References

  1. "Product Information. DaTscan (ioflupane I-123)." GE Healthcare (2022):

DaTscan drug interactions

There are 89 drug interactions with DaTscan (ioflupane I 123).


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.