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Voluven (hydroxyethyl starch) Disease Interactions

There are 5 disease interactions with Voluven (hydroxyethyl starch):

Major

Hydroxyethyl Starch (Includes Voluven) ↔ Coagulation Disorders

Severe Potential Hazard, Moderate plausibility

Applies to: Coagulation Defect, Intracranial Hemorrhage

Do not use hydroxyethyl starch products with preexisting coagulation or bleeding disorders, including those patients with intracranial bleeding.

Major

Hydroxyethyl Starch (Includes Voluven) ↔ Liver Dysfunction

Severe Potential Hazard, Moderate plausibility

Applies to: Liver Disease

Do not use hydroxyethyl starch products in patients with severe liver disease.

Major

Hydroxyethyl Starch (Includes Voluven) ↔ Renal Disease

Severe Potential Hazard, Moderate plausibility

Applies to: Renal Dysfunction

Do not use hydroxyethyl starch products in patients with renal failure with oliguria or anuria not related to hypovolemia, including those patients receiving dialysis treatment.

Major

Hydroxyethyl Starch (Includes Voluven) ↔ Sepsis

Severe Potential Hazard, Moderate plausibility

Applies to: Sepsis

Do not use hydroxyethyl starch products in critically ill adult patients, including patients with sepsis, due to increased risk of mortality and renal replacement therapy.

Major

Hydroxyethyl Starch (Includes Voluven) ↔ Volume Overload

Severe Potential Hazard, Moderate plausibility

Applies to: Hypernatremia

Do not use hydroxyethyl starch products with severe hypernatremia or severe hyperchloremia and in clinical conditions with volume overload.

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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