Twinrix (hepatitis a adult vaccine / hepatitis b adult vaccine) Disease Interactions
There is 1 disease interaction with Twinrix (hepatitis a adult vaccine / hepatitis b adult vaccine):
Hepatitis B Vaccine (Includes Twinrix) ↔ Hemophilia
Moderate Potential Hazard, Moderate plausibility
Applies to: Bleeding Associated with Coagulation Defect
Hepatitis B vaccine (adult and pediatric) is usually for intramuscular administration. However, it may be administered subcutaneously to persons at risk for hemorrhage following intramuscular injections (e.g., hemophiliacs), although it may result in lower antibody response. Additionally, when other aluminum- absorbed vaccines have been administered subcutaneously, an increased incidence of local reactions including subcutaneous nodules has been observed. Therefore, consider subcutaneous administration only in persons who are at risk of hemorrhage following intramuscular injections.
Twinrix (hepatitis a adult vaccine / hepatitis b adult vaccine) drug Interactions
There are 194 drug interactions with Twinrix (hepatitis a adult vaccine / hepatitis b adult vaccine)
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.