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Xiaflex (collagenase clostridium histolyticum) Disease Interactions

There is 1 disease interaction with Xiaflex (collagenase clostridium histolyticum):


Collagenase clostridium histolyticum (Includes Xiaflex) ↔ coagulation disorders

Severe Potential Hazard, Moderate plausibility. Applies to: Coagulation Defect

Collagenase clostridium histolyticum for injection should be avoided in patients with coagulation disorders, including those receiving concomitant anticoagulant medications, other than low-dose aspirin within seven days prior to therapy administration. Care should be exercised if collagenase clostridium histolyticum for injection is used in these patients.

Xiaflex (collagenase clostridium histolyticum) drug interactions

There are 92 drug interactions with Xiaflex (collagenase clostridium histolyticum)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.